The efficacy of Submucosal CO2 Laser in patients with chronic hypertrophic allergic rhinitis
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Abstract
Background: Perennial allergic Rhinitis is a common symptom in otolaryngologic practice. The most effective treatment is avoidance, but in fact this may be very difficult for many patients. Although CO2 laser has been developed for allergic rhinitis treatment but there is still no standard regimen for CO2 laser. Most studies reported that the use of CO2 laser in mucosa layer of inferior turbinate, resulted in mucosal burn and delayed wound healing. In this study, submucosal CO2 laser therapy is used to produce submucosal fibrosis that can reduce allergic reaction for inhaled allergens with low effect on mucociliary function.
Objective: To study submucosal CO2 laser efficacy in treatment of perennial allergic rhinitis patients, mild to moderate symptoms, and analyze by nasal symptom score.
Methods: Prospective randomized control trial. There were 42 eligible subjects with allergic rhinitis patients, 23 males and 19 females, who visited the OPD, Department of Otolaryngology, Somdet Phra Phuttha Loetla Hospital during 1st november 2020 to 31st june 2021. Twenty one random subjects were treated by submucosal CO2 laser, while the rest received usual medical care. The follow-up period were 12 weeks.
Results: By the end of 1st, 3rd, 6th and 12th weeks, outcomes of the submucosal CO2 laser treated group were statistically significantly better than those another group in nasal obstruction, rhinorrhea nasal itching and sneezing symptom
Conclusion: Submucosal CO2 laser is an alternative treatment in patients with mild to moderate symptoms of perennial allergic rhinitis . Submucosal CO2 laser treatment is simple, easy, effective methods, which can be carried out under local anesthesia without major complications.
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