The study of time duration used for diagnosis in the patient with mycosis fungoides: a retrospective study

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Julp Intarasupht

Abstract

Abstract


 


Background


An earlier diagnosis of mycosis fungoides correlates with a better prognosis of the patients. Unfortunately, it’s difficult to early diagnosis because the clinical manifestations are not specific and skin biopsies do not always suggest a definite diagnosis


 


Objective


The study aimed to determine the median duration from the onset of the disease symptoms to the time of diagnosis among patients with mycosis fungoides.


 


Material and methods


A retrospective study included patients who received a diagnosis of mycosis fungoides at Phramongkutklao Hospital from 2010 to 2020


 


Results


The median time needed to diagnose mycosis fungoides was 14 months (interquartile range; 5-48 months). Twelve patients (44.4%) could not confirm the diagnosis of mycosis fungoides in the first attempted skin biopsy. The mean accumulation number of skin biopsies needed to diagnose mycosis fungoides was 2.6 + 1.9 samples. When we compared the patients with early diagnosis (within 12 months) with late diagnosed patients, no difference was found in age, sex and clinical presentation.


 


Conclusions


The median time to diagnose mycosis fungoides was as long as 14 months. Multiple skin biopsy samples are strongly recommended to improve the diagnostic yield.

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นิพนธ์ต้นฉบับ (Original Article)

References

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