Myocardial Scarring Post mRNA-Covid 19-vaccine Related Perimyocarditis
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Abstract
One of the rare possible complications of mRNA-Covid 19-vaccines is acute myocarditis which usually completes clinical recovery, with residual myocardial damage among these patients being rarely reported. Late Gadolinium enhancement technique for cardiac MRI is a unique technique to detect myocardial scaring or focal fibrosis of the myocardium. This case report demonstrates the myocardial scaring detected by the late Gadolinium enhancement technique in a healthy 21-year-old man who was diagnosed with mRNA- Covid 19-vaccine related perimyocarditis and was treated symptomatically. Patient completed recovery and followed up in the 4th month post-recovery with a late Gadolinium enhancement technique cardiac MRI revealing positive Gadolinium enhancement which denoted myocardial scarring.
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References
Witberg G, Barda N, Hoss S, Richter I, Wiessman M, Aviv Y, et al. Myocarditis after Covid-19 Vaccination in a Large Health Care Organization. N Engl J Med. 2021;385(23):2132-9.
Movorach D, Anis E, Cedar N, Bromberg M, Haas ES, Nadir E, et al. Myocarditis after BNT162b2 mRNA Vaccine against Covid-19 in Israel. N Engl J Med. 2021;385(23):2140-9.
Montgomery S, Ryan M, Engler R, Hoffman D, McClenathan B, Collins L, et al. Myocarditis following immunization with mRNA Covid-19 vaccines in members of the US Military. JAMA Cardiol. 2021;6(10):1202-6.
Georgiopoulos G, Figliozzi S, Sanguineti F, Aquaro DG, DiBella G, Stamatelopoulos S, et al. Prognostic Impact of Late Gadolinium Enhancment by Cardiovascular Magnetic Resonance in Myocarditis: A systematic Review and Meta-Analysis. Circ Cardiovasc Imaging. 2021;14:55-65.
Ferreira VM, Schulz-Menger J, Holmvang G, Kramer CM, Carbone I, Sechtem U, et al. Cardiovascular Magnetic Resonance in Nonischemic Myocardial Inflammation: Expert Recommendations. J Am Coll Cardiol. 2018;72(24):3158-76.
Jain SS, Anderson SA, Steele J, Wilson H, Muniz JC, Soslow J, et al. Cardiac manifestations and outcomes of COVID-19 vaccine-associated myocarditis in the young in the USA: longitudinal results from the Myocarditis After COVID Vaccination (MACiV) multicenter study. EClinicalMedicine. 2024;76:102809.
Amir G, Rotstein A, Razon Y, Beyersdorf GB, Barak-Corren Y, Godfrey ME, et al. CMR Imaging 6 Months After Myocarditis Associated with the BNT162b2 mRNA COVID-19 Vaccine. Pediatric Cardiology. 2022;43(7):1522-9.
Kravchenko D, Isaak A, Mesropyan N, Bischoff LM, Pieper CC, Attenberger U, et al. Cardiac magnetic resonance follow-up of COVID-19 vaccine associated acute myocarditis. Front Cardiovasc Med. 2022;9:1049256.