Risk factors of carbapenem-resistant enterobacteriaceae infection

Authors

  • Benjawan Comhangpol Master of Public Health, Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakonnakhon Province Campus
  • Anusak Kerdsin Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakonnakhon Province Campus
  • Peechanika Chopjitt Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakonnakhon Province Campus
  • Chacrit knankhaeng Faculty of Public Health, Kasetsart University, Chalermphrakiat Sakonnakhon Province Campus

Keywords:

Nosocomial infection, carbapenem-resistant Enterobacterales, Enterobacteriaceae

Abstract

This Study to determine risk factor associated with carbapenem-resistant Enterobacteriaceae (CRE) in patients who admitted at Roi Et hospital. The objective of this study was to investigate risk factors of Carbapenem-Resistant Enterobacterales(CRE) infection in patients at Roi Et hospital.

Method: Study design was case-control by divide into CRE-infected patients (case; n=192), carbapenem-susceptible Enterobacteriaceae (CSE) infected patients (control; n=192). Data of these patients were collected during January 1-December 31, 2018.  

Result: the study revealed that most of patients in case group was male (57.3%) and age- mean of 62-year-old (SD=16.67), hospitalization more than 7 days (54.7%). Both control group showed (65.1%), age-mean of 64-year-old (S.D.=13.42), and hospitalization more than 7days (59.9%), respectively. Analysis comparison among case and control group demonstrated that male (ORAdj=2.35, 95%CI=1.76-3.14), age >60 year-old (ORAdj=2.35,95%CI =1.76-3.14), hospitalization >7 days (ORA dj=2.00,95%CI=1.50-2.66), received carbapenem before admit (ORAdj=3.31, 95%CI =2.46-4.46), received carbapenem during hospitalization (ORAdj=3.69, 95%CI=2.74-4.98), blood received (ORAdj= 2.52,95%CI= 1.88-3.38), ventilation association (ORAdj=2.64, 95%CI=1.97-3.54), ventilation used >7days (ORAdj=3.38,95%CI=2.43-4.71), surgery (ORAdj=2.20;95%CI:1.61-3.02), intravenous injection (ORAdj=4.19;95%CI:3.10-5.66), and >7 days (ORAdj =3.50;95% CI:2.53-4.86), utilization of urinary catheter (ORAdj=2.26,95%CI=1.68-3.02), and>7days (ORAdj=3.60,95%CI =2.57-5.05) were the risk factors of CRE infection. 

            Conclusions: This study found out that risk factors of CRE infection were Carbapenems treatment, underwent with ventilation, catheterization, blood transfusion, surgery, Central Venous Catheter, and utilization of urinary catheter.

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Published

2022-12-27

How to Cite

Comhangpol, B., Kerdsin, A. ., Chopjitt, P., & knankhaeng, C. . (2022). Risk factors of carbapenem-resistant enterobacteriaceae infection. UBRU Journal for Public Health Research, 11(2), 79–89. Retrieved from https://he02.tci-thaijo.org/index.php/ubruphjou/article/view/254654

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ORIGINAL ARTICLES