The Effects of Oral Zinc on The Level Changes of Total Testosterone and Estradiol among Fat Male who Having Body Mass Index more than 30 kg/m2

Abstract

Objective: To examine the effect of Chelated Zinc on the changes in Total Testosterone, Estradiol (Estradiol / Total Testosterone Ratio).

Methods: This was a experimental, prospective, randomize, double blinded, placebo-controlled among 45 soldiers of 5th Antiaircraft Artillery Battalion, 1st Antiaircraft Artillery Regiment who were more than 40 years old and had BMI more than 30 kg/m2. This research spent 12 weeks. This experimental group obtained Chelated Zinc 15 mg/tablet, and they ate 4 tablets every morning. 

Results: The experimental results showed that most of experimental group were 50-59 years old (58.3%), followed by those aged 40-49 years old (25.0%). They had underlying diseases, such as hypertension (66.7%), followed by gout (33.3%). There were 33.3% of experimental group who had people in their families had underlying diseases and the drug use history. Most of them took medicines for the hypertension treatment and uricosuria drugs (40.0%). Most of the control group were 50-59 years old. They were as same as the experimental group (58.3%), next, they were 40-49 years old (41.1%). Most of them hadn’t any underlying diseases (66.7%) and 8.3% of them took medicines and Chelated Zinc which had the effect to BMI with the statistical significance (P<0.001).

Conclusion: The findings would be beneficial as another way to protect and decrease the risk of cardiovascular disease among men who in the risk (over 40 years old and fat). For the next experiment, the researcher would study the relative factors and the side effects of Chelated Zinc taking in people who were in the risk of cardiovascular disease for being the information about the quantity defining of the Chelated Zinc taking of each individual suitably and the risk would be decreased.