The effect of hand and foot exercises training on symptoms of numbness in colorectal cancer patients receiving oxaliplatin via peripheral intravenous administration
Article Sidebar
Main Article Content
Abstract
This experimental study aims to examine the effect of hand and foot exercise training on numbness symptoms in colorectal cancer patients receiving oxaliplatin via peripheral intravenous administration. The sample comprises patients diagnosed with colorectal cancer who receive care at Mahavajiravudh Ward 6A of Vajira Hospital. A total of 52 eligible participants were selected using a block selection method and divided into two groups of 26 participants each. The control group received standard nursing care, while the experimental group participated in hand and foot exercise training. Numbness symptoms were assessed using a measurement tool developed from a review of relevant literature. Data analysis included descriptive statistics, such as percentage, mean, and standard deviation, along with t-tests for hypothesis testing and analysis of covariance (ANCOVA) to assess variance
The research results revealed that pre-exercise numbness scores significantly influenced post-exercise numbness scores (F(1, 49) = 164.12, p < .001). After adjusting for the effect of pre-exercise scores, the experimental group that received hand and foot exercise training showed a statistically significant reduction in post-exercise neuropathy symptoms compared to the control group (F(1, 49) = 39.81, p < .001). This study indicates that hand and foot exercise training can effectively alleviate numbness symptoms associated with oxaliplatin treatment in colorectal cancer patients.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวชิรสารการพยาบาลถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรง ซึ่งกองบรรณาธิการไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใด ๆ ทั้งสิ้น
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวชิรสารการพยาบาล ถือเป็นลิขสิทธิ์ของวชิรสารการพยาบาล หากบุคคลใดหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใด ๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากวชิรสารการพยาบาลก่อนเท่านั้น
References
สถาบันมะเร็งแห่งชาติ กรมการแพทย์ กระทรวงสาธารณสุข. คู่มือมาตรฐานการทำงานเกี่ยวกับยาเคมีบำบัดและการดูแลผู้ป่วยหลังได้รับยา. กรุงเทพมหานคร: นิวธรรมดาการพิมพ์; 2560.
Zajaczkowska R, Kocot-Kepska M, Leppert W, Wrzosek A, Mika J, Wordliczek J. Mechanisms of chemotherapy-induced peripheral neuropathy. Int J Mol Sci. 2019;20(6):1451.
Hsu SY, Huang WS, Lee SH, Chu TP, Lin YC, Lu CH, et al. Incidence, severity, longitudinal trends and predictors of acute and chronic oxaliplatin-induced peripheral neuropathy in Taiwanese patients with colorectal cancer. Eur J Cancer Care (Engl). 2019;28(2).
Stefansson M, Nygren P. Oxaliplatin added to fluoropyrimidine for adjuvant treatment of colorectal cancer is associated with long-term impairment of peripheral nerve sensory function and quality of life. Acta Oncol. 2016;55(9-10):1227-1235.
Loprinzi CL, Lacchetti C, Bleeker J, Cavaletti G, Chauhan C, Hertz DL, et al. Prevention and management of chemotherapy-induced peripheral neuropathy in survivors of adult cancers: ASCO guideline update. J Clin Oncol. 2020;38(28):3325-3348.
Maihöfner C, Diel I, Tesch H, Quandel T, Baron R. Chemotherapy-induced peripheral neuropathy (CIPN): current therapies and topical treatment options with high-concentration capsaicin. Support Care Cancer. 2021;29(8):4223-4238.
Introntakun K, Silaguntsuti C, Vittayatigonnasak A, Supawattanaobodee B, Parklug P. Effect of discharge planning for colorectal cancer patients using patterns METHOD-P on the knowledge of adverse reactions management after receiving chemotherapy. Vajira Nurs J. 2020;22(1):1-14.
Ladawan A, Petpichetchian W, Wiroonpanitch W. A survey of common symptoms of cancer patients in southern Thailand. Songkla Med J. 2011;23:134-142.
Natasonti A, Limamnuaylap S. Symptoms and symptom management of cancer patients receiving chemotherapy. J Nurs Health. 2009;32(1):12-24.
Panya-Inkaew P. Peripheral neuropathy from chemotherapy: Symptom management and patient outcomes. [Master's thesis]. Bangkok: Mahidol Univ.; 2019.
Malangphuethong R, Pongthavornkamol K, Sriyuktasuth A, Soparatnaphisal N. Symptom experiences, management strategies, and functional status in advanced lung cancer patients receiving chemotherapy. J Nurs Sci. 2009;27(2) :69-78.
Suedi N, Pongthavornkamol K, Sriyuktasuth A, Sirithanaratnakul N. Symptom experiences and their effects on functional status in hematologic cancer patients receiving chemotherapy. J Nurs Sci. 2015;33(2):29-40.
Pudtong N, Aungsuroch Y, Jitpanya C. Symptom clusters in Thai patients with advanced lung cancer. J Nurs Sci. 2014;28:183-189.
Khamboon T, Pongthavornkamol K, Olson K, Wattanakitkrileart D, Viwatwongkasem C, Lausoontornsiri W. Symptom experiences and symptom cluster across dimensions in Thais with advanced lung cancer. Pac Rim Int J Nurs Res. 2015;19(4):330-344.
Thanakun P, Jitpanya C, Padtong N. Peripheral neuropathy induced by chemotherapy in breast cancer patients and associated factors. J Royal Thai Army Med. 2020;73(4):243-252.
Sabumnet S, Seneha J, Puangkaew A, Soparatnaphisal N. Predicting factors of chemotherapy-induced peripheral neuropathy in colorectal cancer patients treated with chemotherapy. J Police Nurs. 2022;14(2):268-277.
Chaichan P, Methakanjanasak N. Peripheral neuropathy experiences in colorectal cancer patients receiving chemotherapy. J Nurs Care Health. 2020;38(2):24-32.
Watchra K, Seneha J, Pongthavornkamol K, Gorpaisal K. The effect of temperature control at oxaliplatin administration site on venous pain in colorectal cancer patients. J Nurs Council. 2021;36(3):103-117.
Simsek NY, Demir A. Cold application and exercise on development of peripheral neuropathy during taxane chemotherapy in breast cancer patients: A randomized controlled trial. Asia Pac J Oncol Nurs. 2021;8(3):255-266.
Kleckner IR, Kamen C, Gewandter JS, Mohile NA, Heckler CE, Culakova E, et al. Effects of exercise during chemotherapy on chemotherapy-induced peripheral neuropathy: A multicenter, randomized controlled trial. Support Care Cancer. 2018;26(4):1019-1028.
Lopez G, Eng C, Overman M, Ramirez D, Liu W, Beinhorn C, et al. A randomized pilot study of oncology massage to treat chemotherapy-induced peripheral neuropathy. Sci Rep. 2022;12(1):19023.
Ikio Y, Sagari A, Nakashima A, Matsuda D, Sawai T, Higashi T. Efficacy of combined hand exercise intervention in patients with chemotherapy-induced peripheral neuropathy: A pilot randomized controlled trial. Support Care Cancer. 2022;30(6):4981-4992.
Nunez de Arenas-Arroyo S, Cavero-Redondo I, Torres-Costoso A, Reina-Gutiérrez S, Lorenzo-García P, Martínez-Vizcaíno V. Effects of exercise interventions to reduce chemotherapy-induced peripheral neuropathy severity: A meta-analysis. Scand J Med Sci Sports. 2023;33(7):1040-1053.
Bao T, Seidman AD, Piulson L, Vertosick E, Chen X, Vickers AJ, et al. A phase IIA trial of acupuncture to reduce chemotherapy-induced peripheral neuropathy severity during neoadjuvant or adjuvant weekly paclitaxel chemotherapy in breast cancer patients. Eur J Cancer. 2018;101:12-19.
Oh PJ, Kim YL. Effectiveness of non-pharmacologic interventions in chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis. J Korean Acad Nurs. 2018;48(2):123-142.
Rithirangsriroj K, Manchana T, Akkayagorn L. Efficacy of acupuncture in prevention of delayed chemotherapy-induced nausea and vomiting in gynecologic cancer patients. Gynecol Oncol. 2015;136(1):82-86.
Kayıkcı EE, Can G. The effect of salt-water bath in the management of treatment-related peripheral neuropathy in cancer patients receiving taxane and platinum-based treatment. EXPLORE. 2021;18:54-60.
Lin JX, Chen ZH, Chen XW, Fan ZY, Huang XY, Li X. The effect of bundle of warmth care for patients with advanced colorectal cancer undergoing chemotherapy on reduction of oxaliplatin-related peripheral sensory neuropathy. J Clin Oncol. 2017;35 (15 Suppl).
Pimbueng N, Wattana C, Harnirattisai T. Effect of a symptom management program on symptom severity and nutritional status in colorectal cancer patients receiving chemotherapy. J Nurs Sci. 2015;42:73-83.
