IMRT/VMAT in Nasopharyngeal Carcinoma Patients : An Analysis of 33 Cases

Authors

  • T Chottetanaprasith Ubonratchatani Cancer Hospital

Keywords:

Nasophayngeal carninoma, IMRT, VMAT

Abstract

Nasopharyngeal carcinoma is common cancer in Southeast Asia and Thailand. IMRT (Intensity-modulated radiation therapy) and VMAT (Volumetric modulated arc therapy) are advanced techniques radiotherapy in the treatment of nasopharyngeal carcinoma. This study aimed to evaluate efficacy in the treatment of nasopharyngeal carcinoma with IMRT/VMAT at Ubonratchatani cancer hospital from July 2014 to December 2016. The data were reviewed including demographic data, pathological finding, stage of the tumor, radiation techniques, radiation doses to target volumes, radiation doses to normal organs, responses of treatment, survival rate and toxicities. Thirty-three patients were recruited. The result was found that 81.8% of patients had VMAT treatment and most of the patients use SIB technique 93.9%. After treatment, 69.7% and 30.3% of the patients had a complete and partial response, respectively. Median follow up period was 42 months. The 3-year progression-free survival was 72.7% and 3-year overall survival was 81.8%. Most toxicities were not severe. Acute side effect grade 1 and 2 mucositis were found 36.4% and 63.6% respectively. The common side effect was grade 1 xerostomia (57.6%) and grade 2 xerostomia (24.2%). From this study, we can achieve good results with high survival rate and acceptable toxicities when treating nasopharyngeal carcinoma patients with IMRT/VMAT.

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Published

30-12-2019

How to Cite

1.
Chottetanaprasith เ. IMRT/VMAT in Nasopharyngeal Carcinoma Patients : An Analysis of 33 Cases. j dept med ser [Internet]. 2019 Dec. 30 [cited 2022 Aug. 18];44(6):61-8. Available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/244796

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Original Article