Analysis of Cerebrospinal Fluid Flow Quantification though Aqueduct of Sylvius using Phase Contrast Cine MR Imaging


  • Sarayut Wonglao, B.Sc. Department of Radiology, Neurological institute of Thailand


Normal Pressure Hydrocephalus (NPH), CSF flow, Phase contrast cine MR Imaging, Aqueduct of sylvius


Background: Neurological institute of Thailand has a high frequency of cerebrospinal fluid (CSF flow) quantification through aqueduct of sylvius so we were performed the difference region of interest (ROI) measurement comparable to standard while doesn’t take a long time of post-processing.Objective: To evaluate compare the results of each ROI measurement and post-processing time to standard.Method: The retrospective study of the 50 patients with and without suspected Normal Pressure Hydrocephalus (NPH) who had 2D Phase Contrast cine MR Imaging with MRI 3T since 2015-2017 from PACS in Radiology Department. The analysis of CSF flow measurement has different ROI measurement include ROI 1 was performed automatic measurement in a circular ROI, manual measurement for ROI 2 that allows to standard, 50%, 75%, 25% manual measurement of the data for the ROI 3, 4, 5 in order and copy contours for the ROI 6. The ANOVA test was used to compare the values obtained each ROI measurement with the SPSS statistical.Results: The values of the ROI 3, 4 and 6 were not statistically significant to the ROI 2 and the ROI 6 was used post-processing time less than other ROI measurement.Conclusion: The ROI 6 was performed comparable precision to standard and shorter post processing time.


Download data is not yet available.


Charnchaowanish P, Chawalparit O, Tisavipat N, Suthipongchai S.Reliability Study in Quantitative Analysis of MRI CSF Flow Study.Thai Journal of Radiological Technology 2004; 29: 1-4.

Kapsalaki E, Tsougos I, Svolou P, Dardiotis E, Hadjigeorgiou G,Fountas KN. Normal CSF Flow Measurement at the Aqueduct performed at 3T. XIX Symposium Neuroradiologicum, Bologna:Italy; 2010.

Lee JH, Lee HK, Kim JK, Kim HJ, Park JK, Choi CG. CSF flow quantification of the cerebral aqueduct in normal volunteers using phase contrast cine MR imaging. Korean J Radiol 2004; 5:81-6.

Unal O, Kartum A, Avcu S, Etlik O, Arslan H, Bora A. Cine phase-contrast MRI evaluation of normal aqueductal cerebrospinal fluid flow according to sex and age. Diagn Interv Radiol 2009; 15: 227-31.

Ringstad G, Emblem KE, Geier O, Alperin N, Eide PK. Aqueductal Stroke Volume: Comparisons with Intracranial Pressure Scores in Idiopathic Normal Pressure Hydrocephalus. AJNR Am J Neuroradiol 2015;36:1623-30.

Bradley WG Jr. CSF Flow in the Brain in the Context of Normal Pressure Hydrocephalus. AJNR Am J Neuroradiol.2015; 36:831-8.

Questions and Answers in MR. Velocity Encoding (VENC).(Internet). (cited 2014 Aug 1).Available from:http// Velocity Encoding (VENC).htm.



How to Cite

Wonglao S. Analysis of Cerebrospinal Fluid Flow Quantification though Aqueduct of Sylvius using Phase Contrast Cine MR Imaging. j dept med ser [Internet]. 2021 Nov. 30 [cited 2023 Jan. 29];46(3):15-22. Available from:



Original Article