A Case Report of Worsening Pancytopenia in a Patient with Evans Syndrome During a COVID-19 Infection
Keywords:
Evans syndrome, COVID-19, PancytopeniaAbstract
In 2019, a coronavirus called SARS-CoV-2 was first discovered as a cause of adeadly pneumonia in China, before spreading worldwide leading to global COVID-19 pandemic. Major manifestations of the disease arefever and respiratory symptoms, with possible consequences of acute respiratory distress syndrome, thromboembolism, and multi-organ failure in severe cases. In addition to respiratory manifestations, hema- tologic complications have also been affecting patients with COVID-19 infections. This includes cytopenias, hemolysis and abnormal coagulation. Cases of newly diagnosed Evans syndrome have also been reported to occur both after and concomitantly with COVID-19 infections. In this case report, we present a case of Evans syndrome developing intopancytopenia during aCOVID-19 infection. A 48 year-old man with Evans syndrome was admitted due to acute fever and dark urine. He was positive for COVID-19 infection and his laboratory investigations showed pancytopenia withacute hemolysis. Remdesivir was given along with systemic glucocorticoid. This resulted in an overall improvement of cytopenias and his clinical status.
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