Congenital Associated Malformations in Patients with Cleft Lip and Palate at Rajavithi Hospital

Authors

  • Rattiya Chuacharoen Dental Department, Rajavithi Hospital

Keywords:

Cleft lip and palate, Congenital malformation, Deformation, Anormaly

Abstract

Background: Orofacial clefts are often associated with other congenital malformations. Previous studies have reported varying incidences and types of anomalies. In Thailand, there has been no reported data on these associations in infants with cleft lip and/or cleft palate. Objective: To report the prevalence of congenital malformations occurring in conjunction with orofacial clefts from birth and to detail the number of cleft lip and/or cleft palate infants treated at Rajavithi Hospital. Methods: This was a descriptive study. It involved surveying the entire population of newborns with cleft lip and/or palate from the medical records of Rajavithi Hospital, covering births from April 2014 to February 2023. The diagnosis was based on the International Classification of Diseases (ICD-10-TM). Results: Out of 118 infants with orofacial clefts, the male-to-female ratio was 1:1. Among these, 35 infants (29.7%) had additional congenital malformations. Infants with isolated cleft palate had the highest rate of associated malformations, with 9 (36%) cases. The most common additional malformation was congenital anomalies of the digestive system, observed in 14 (11.9%) cases, all of which included ankyloglossia (tongue-tie). Conclusion: A comprehensive understanding of the congenital malformations associated with orofacial clefts is crucial for further diagnostic testing, genetic counseling, and holistic care of cleft lip and/or cleft palate patients.

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Published

17-03-2025

How to Cite

1.
Chuacharoen R. Congenital Associated Malformations in Patients with Cleft Lip and Palate at Rajavithi Hospital. J DMS [internet]. 2025 Mar. 17 [cited 2025 Mar. 20];50(1):122-30. available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/270574

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Original Article