Association between Bone Mineral Density, Panoramic Radiographic Indices of the Mandible, and Tooth Loss in Dental Patients at a Tertiary Hospital

Authors

  • Chulamanee Sookprome Rajavithi Hospital

Keywords:

Bone mineral density, Panoramic radiographic indices, Tooth loss

Abstract

Background: Previous studies have shown the association between decreased bone mineral density and changes in mandibular bone structure. This has led to increased interest in investigating the relationship between osteoporosis, panoramic radiographic imaging and tooth loss. Panoramic radiographs which commonly used in dentistry are considered a useful and cost-effective screening tool for identifying patients at risk for osteoporosis. Objective: To examine the association between bone mineral density (BMD), tooth loss and three panoramic radiographic indices of mandible (panoramic mandibular index-PMI, mental index-MI, and mandibular cortical index-MCI) in dental patients. Methods: This cross-sectional study included 125 patients who had an oral examination and were treated at Rajavithi Hospital during the period from January 2024 to August 2025. Inclusion criteria were the patients with no history of fractures and no prior use of osteoporosis. All participants had undergone bone mineral density (BMD) assessment and digital panoramic radiographic imaging. BMD T-score and parameters such as PMI, MI, MCI, and tooth loss were measured. The independent t-test, One-Way ANOVA and Pearson correlation were analyzed. Results: A total 125 dental patients in this research were 13 males (10.4%) and 112 female (89.6%), age from 50 to 89 years. This study found a significant association between BMD T-score and panoramic radiographic indices of mandible (MI, MCI) and
tooth loss (p-value < .05). However, BMD T-score was not significantly associated with PMI. Conclusions: These findings of this study suggest that in patients’ panoramic radiographic indices (MI, MCI indices) and tooth loss may be a useful index for screening osteoporosis. Bone mineral density (BMD) measurement by dual-energy X-ray absorptiometry (DEXA) remains the method for screening osteoporosis.

References

National Statistical Office. The 2024 report: survey of the older persons in Thailand [Internet]. Bangkok: Ministry of Digital Economy and Society; 2024 [cited 2025 Jan 9]. Report No.: ISSN 1906-2869. Available from: https://www.nso.go.th/nsoweb/nso/survey_detail/iM?set_lang=en

Kanis JA. An update on the diagnosis of osteoporosis. Curr Rheumatol Rep 2000;2(1):62-6.

Jeffcoat M. The association between osteoporosis and oral bone loss. J Periodontol 2005;76(11 Suppl):2125-32.

Erdem RZ, Erdem M, Kıranatlı M, Karakaya K. Relationship between bone mineral density and oral health: a cross sectional observational study. BMC Oral Health 2025;25(1):250.

Xu S, Zhang G, Guo JF, Tan YH. Associations between osteoporosis and risk of periodontitis: A pooled analysis of observational studies. Oral Dis 2021;27(2):357-69.

Darcey J, Horner K, Walsh T, Southern H, Marjanovic EJ, Devlin H. Tooth loss and osteoporosis: to assess the association between osteoporosis status and tooth number. Br Dent J 2013;214(4):E10.

Benson BW, Prihoda TJ, Glass BJ. Variations in adult cortical bone mass as measured by a panoramic mandibular index. Oral Surg Oral Med Oral Pathol 1991;71(3):349-56.

Klemetti E, Kolmakov S, Kröger H. Pantomography in assessment of the osteoporosis risk group. Scand J Dent Res 1994;102(1):68-72.

Kinalski MA, Boscato N, Damian MF. The accuracy of panoramic radiography as a screening of bone mineral density in women: a systematic review. Dentomaxillofac Radiol 2020;49(2):20190149.

Alam T, AlShahrani I, Assiri KI, Almoammar S, Togoo RA, Luqman M. Evaluation of Clinical and Radiographic Parameters as Dental Indicators for Postmenopausal Osteoporosis. Oral Health Prev Dent 2020;18(3):499-504.

Kiswanjaya B, Priaminiarti M, Bachtiar-Iskandar HH. Three panoramic indices for identification of healthy older people at a high risk of osteoporosis. The Saudi Dental Journal 2022;34(6):503-8.

Taguchi A, Suei Y, Ohtsuka M, Otani K, Tanimoto K, Ohtaki M. Usefulness of panoramic radiography in the diagnosis of postmenopausal osteoporosis in women. Width and morphology of inferior cortex of the mandible. Dentomaxillofac Radiol 1996;25(5):263-7.

Pornsathapant D. Relationship between osteoporosis and indices of mandible from panoramic radiograph. J DMS 2019;44(6):106–11.

Chongruangsri N, Jansisyanont P, Chuenchompoonut V, Amphansap T, Stitkitti N. Digital panoramic radiographic indices correlated with BMD status. J Dent Assoc Thai 2021;71(3):194–204.

Marandi S, Bagherpour A, Imanimoghaddam M, Hatef M, Haghighi A. Panoramic-based mandibular indices and bone mineral density of femoral neck and lumbar vertebrae in women. J Dent (Tehran) 2010;7(2):98-106.

Nakamura N, Otsuru M, Miyoshi T, Suyama K, Omori K, Morishita K, et al. Risk factors for the development of medication-related osteonecrosis of the jaw and effects of tooth extraction with local infection. J Dent Sci 2024;19(3):1770-82.

Lorenzo-Pouso AI, Pérez-Sayáns M, Chamorro-Petronacci C, Gándara-Vila P, López-Jornet P, Carballo J, et al. Association between periodontitis and medication-related osteonecrosis of the jaw: A systematic review and meta-analysis. J Oral Pathol Med 2020;49(3):190-200.

Sokal RR, Rohlf FJ. Introduction to biostatistics. 2nd ed. New York: Dover Publications; 2009.

Papapanou PN, Sanz M, Buduneli N, Dietrich T, Feres M, Fine DH, et al. Periodontitis: Consensus report of workgroup 2 of the 2017 World Workshop on the Classification of Periodontal and Peri-Implant Diseases and Conditions. J Periodontol 2018;89 Suppl 1:S173-82.

Salari N, Ghasemi H, Mohammadi L, Behzadi MH, Rabieenia E, Shohaimi S, et al. The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis. J Orthop Surg Res 2021;16(1):609.

Horner K, Devlin H, Harvey L. Detecting patients with low skeletal bone mass. J Dent 2002;30(4):171-5.

Taguchi A, Suei Y, Sanada M, Ohtsuka M, Nakamoto T, Sumida H, et al. Validation of dental panoramic radiography measures for identifying postmenopausal women with spinal osteoporosis. AJR Am J Roentgenol 2004;183(6):1755-60.

Damanaki A, Habel ML, Deschner J. Association of Osteoporosis with Tooth Loss and Dental Radiomorphometric Indices. Biomedicines 2024;12(12):2886.

Sözen T, Özışık L, Başaran N. An overview and management of osteoporosis. Eur J Rheumatol 2017;4(1):46-56.

Klemetti E, Collin HL, Forss H, Markkanen H, Lassila V. Mineral status of skeleton and advanced periodontal disease. J Clin Periodontol 1994; 21(3):184-8.

Downloads

Published

18-03-2026

How to Cite

1.
Sookprome C. Association between Bone Mineral Density, Panoramic Radiographic Indices of the Mandible, and Tooth Loss in Dental Patients at a Tertiary Hospital. J DMS [internet]. 2026 Mar. 18 [cited 2026 Mar. 20];51(1):138-45. available from: https://he02.tci-thaijo.org/index.php/JDMS/article/view/277952

Issue

Section

Original Article