Patterns of hematological parameter among Dengue Hemorrhagic Fever patients in Suratthani Hospital detected by Coulter LH780

Abstract

Clinical diagnosis for Dengue Hemorrhagic Fever ( DHF) should be diagnosed together with symptoms and the changing of hematological parameters. The study was a retrospective cohort study from 175 DHF patients in Suratthani Hospital who positive for either dengue NS1 Antigen or anti-dengue IgM, or/and I gG antibodies were analyzed. These samples were collected from October 2015 to September 2016 This study was classified the positive serological patterns into six groups: 1).NS1Ag Positive 2).NS1Ag and IgM Positive 3).NS1Ag and IgG Positive 4).NS1Ag,IgM and IgG Positive 5).IgM Positive 6).IgM and IgG Positive and then compared the hematological data with healthy people . The results showed that the means and standard deviations of white blood cells and platelet level from DHF patients with positive dengue NS1 Antigen anti-dengue IgM and IgG were decreased (p<0.05) when compared with control group, In additional the increased of monocyte and atypical lymphocyte levels were present in this study. These finding indicate that the clinical history and
hematological parameters in dengue viral infection such as decreased of white blood cells and platelet levels and increase of monocyte and atypical lymphocyte levels are an important part of diagnostic of patients.