The Association between Antibiotics Used and Risk of Multidrug resistant Pseudomonas aeruginosa Infection
Keywords:
RoiEt hospital, antibiotics, multidrug resistant, P.aeruginosaAbstract
Objective :To investigated the association between antibiotics used and risk of multidrug resistant P.aeruginosa infection.
Methods : A hospital based case control study (Control:Case = 1:1). Data were collected from medical records of patients at Roi Et hospital between 1January 2014 to 31 December 2015. The descriptive statistic, univariate analysis and multivariate analysis were used to data analysis.
Results : All of 95 cases were male 51.5%, mean age was 61.4 years, SD=+16.2 and all of 95 controls were male 56.8%, mean age was 54.7 years, SD=+16.4. The multivariate analysis found patients age over 60 years (ORAdj.=2.3; 95% CI: 1.24-4.09), admitted more than 7 days (ORAdj.=2.1; 95% CI: 1.45-3.79), patients exposed to 3rd generation cephalosporin (ORAdj.= 3.6; 95% CI: 1.73- 7.31), Cabapenems (ORAdj.=2.9; 95% CI: 1.40-5.92), Tetracycline (ORAdj.=2.2; 95% CI: 1.69-7.06) and Glycopeptides (ORAdj.=2.3; 95%CI : 1.94-5.72) were risk of multidrug resistant P.aeruginosa infection.
Conclusion : The elderly patients, long time hospitalization patients and patients were exposed some types of antibiotics were risk factors of multidrug resistant P.aeruginosa infection.
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