ลักษณะทางคลินิกและความรุนแรงของโรคไข้หวัดใหญ่ในเด็กที่เข้ารับการรักษาใน โรงพยาบาลชุมพรเขตรอุดมศักดิ์

Naiyana Boontan

Authors

Naiyana Boontan Chumphon Khet Udomsak Hospital

Keywords:

Influenza A, Risk factors, Oseltamivir

Abstract

Background: Influenza is a major cause of morbidity and hospitalization among children, particularly in young children and those with underlying diseases. However, data on the clinical characteristics and severity of influenza in Chumphon province remain limited.
Objectives: To investigate the clinical characteristics, severity, and factors associated with severe influenza among pediatric patients admitted to Chumphon Khet Udomsak Hospital.
Methods: This retrospective cohort study reviewed the medical records of children aged <15 years with laboratory-confirmed influenza who were admitted to Chumphon Khet Udomsak Hospital between January 1 and December 31, 2025. Data was analyzed using descriptive statistics, comparative analyses, and multivariable logistic regression.
Results: A total of 348 patients were included. Influenza A accounted for 73.0% of cases, and 29.3% developed severe influenza. Factors significantly associated with severe influenza included age <12 months (adjusted OR = 4.29), presence of underlying disease (adjusted OR = 2.22), prematurity (adjusted OR = 3.57), tachypnea (adjusted OR = 71.79), and delayed antiviral treatment more than 48 hours after symptom onset (adjusted OR = 2.00).
Conclusions: Severe influenza was observed in approximately one-third of hospitalized children. Important risk factors associated with severe disease included age <12 months, underlying disease, prematurity, tachypnea, and delayed antiviral therapy.

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