Development of lentigines and melanocytic nevi within segmental nevus depigmentosus: A case report
Keywords:
Nevus depigmentosus, lentigines, melanocytic neviAbstract
Nevus depigmentosus (ND) is an uncommon congenital nonprogressive, hypopigmented macule or patch that remains stable in size and distribution throughout life, resulted from a defect of melanosomes transfer from melanocytes to keratinocytes. Multiple lentigines or pigmented nevi occurring within nevus depigmentosus are considered a rare phenomenon. Somatic revertant mosaicism may be the plausible explanation. We report a 12-year-old girl who presented with a hypopigmented patch on the right neck and shoulder since birth. There has been a progressively increasing in number of macules and patches that varied from light to dark brown within the area of leukoderma for six years. Histopathology from a dark brown spot showed elongated rete ridges with slightly enlarged nevus cells and mild lamellar fibrosis, which were consistent with dysplastic nevus.
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เนื้อหาและข้อมูลในบทความที่ลงตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นข้อคิดเห็นและความรับผิดชอบของผู้เขียนบทความโดยตรงซึ่งกองบรรณาธิการวารสาร ไม่จำเป็นต้องเห็นด้วย หรือร่วมรับผิดชอบใดๆ
บทความ ข้อมูล เนื้อหา รูปภาพ ฯลฯ ที่ได้รับการตีพิมพ์ในวารสารโรคผิวหนัง ถือเป็นลิขสิทธิ์ของวารสารฯ หากบุคคลหรือหน่วยงานใดต้องการนำทั้งหมดหรือส่วนหนึ่งส่วนใดไปเผยแพร่ต่อหรือเพื่อกระทำการใดๆ จะต้องได้รับอนุญาตเป็นลายลักอักษรจากบรรณาธิการวารสารโรคผิวหนังก่อนเท่านั้น
