Sepsis recognition in caregivers: A comparison between time of arrival to an emergency department and clinical outcomes of patients in Somdech Phra Pinklao hospital
Keywords:
Sepsis, Time-to-Treatment, MorbidityAbstract
Introduction : Sepsis can cause morbidity and mortality if it is not treated properly. Time to treatment has been found to affect the severity and mortality of sepsis in previous research. However, there have been no studies comparing arrival time to clinical outcome.
Objectives : Compare the length of sepsis patients' symptoms to the morbidity and mortality of patients brought to the emergency department.
Methods : A descriptive retrospective study, Somdej Phra Pinklao Hospital.
Results : 288 patients with sepsis from medical records. The baseline characteristics of the patients were not different. The duration of symptoms had no effect on morbidity (mean 1,440 and 1,940 minutes in non-morbidity and morbidity groups, respectively, p-value 0.061) and mortality (mean 1,440 and 1,440 minutes in non-mortality and mortality groups,respectively, p-value 0.414). However, the following factors were found to increase morbidity and mortality, including altered mental status (30.65% and 42.68% in non-morbidity and morbidity groups, respectively, p-value 0.037) (30.84% and 56.76% in non-mortality and mortality groups, respectively, p-value <0.001) shortness of breath(19.35% and 40.85% in non-morbidity group and morbidity groups, respectively, p-value<0.001) (28.04% and 41.89% in non-mortality and mortality groups, respectively, p-value<0.027). In contrast, factors that reduce the risk were fever or chills (70.16% and 50.61% in non-morbidity and morbidity groups, respectively, p-value 0.001) (65.42%6 and 40.54% in non-morbidity group and mortality groups, respectively, p-value <0.001)
Conclusion : The duration of symptoms did not affect the clinical outcomes, however fever or chills did lower the risk. Shortness of breath and altered mental status both increased the risk of sepsis and mortality.
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