lntraoperative Mitomycin C in Pterygium Excision

Abstract

lntraoperative Mitomycin C in Pterygium Excision

Vichai Hanbunchong  MD

Department of Ophthalmology, BMA Medical College and Vajira Hospital

Objective: To study the effectiveness of intraoperative mitomycin C in pterygium excision and the postoperative complications.

Study design: Non-randomized clinical trial.

Subjects: Ninety primary pterygia were studied from January 1998 to September 1999 at the Department of Ophthalmology, BMA Medical College and Vajira Hospital.

Methods: Ninety primary pterygia were non-randomized to two groups : simple excision (40 pterygia). and

intraoperative mitomycin 0.4 mg/ml for 3 minutes (50 pterygia). Study the effectiveness and complications  of these two techniques.

Main outcome measures: Recurrence of pterygium and postoperative complications were measured.

Results: The recurrence rates in simple excision and intraoperative mitomycin  were

78.7 %, and 6.1 %. respectivey with statistically significant difference (p = 0.01). There was no serious complication in both two groups.

Conclusion: Intraoperative mitomycin C was a effective adjunct to surgical excision in the treatment of primary pterygium.

Key words: pterygium, intraoperative mitomycin C

Vajira Med J 2001 ; 45 : 41 - 46