Resistant Trends of Antimicrobial Agents in Urinary Tract Infection

Abstract

Resistant Trends of Antimicrobial Agents in Urinary Tract Infection

Uraporn Phumisantiphong     BSc (Med Tech)

Department of Central Laboratory, BMA Medical College and Vajira Hospital

Objective : To study the causative organisms in urinary tract infection and the trends of antimicrobial resistance in BMA Medical College and Vajira Hospital.

Study design : Descriptive study.

Subjects : Urine samples were collected from patients in BMA Medical College and Vajira Hospital requested for urine culture during January 1998 to December 2000.

Methods : Urine samples were cultured on blood agar and Mac Conkey agar. The suspected bacterial colonies were selected and identified by biochemical test and susceptibility test of the organisms for study the trends of resistance.

Main outcome measures : The percentage of causative organisms and antimicrobial susceptibility of the organisms in urinary tract.

Results : Escherichia coli was the most frequent isolated in urinary tract infection (26.65%) followed by Candida albicans (17.15%), Pseudomonas aeruginosa (12.14%), Enterococcus species (8.68%). Klebsiella pneumoniae(7.44%) and Proteus mirabilis (3.29%). The increasing resistance to norfloxacin and nitrofurantoin were observed in Escherichia coli and norfloxacin in Klebsiella pneumoniae.

Conclusion : Escherichia coli was the most frequent isolated with increasing trend in antimicrobial resistance.

Key words : urinary tract infection, antimicrobial susceptibility

Vajira Med J 2001 ; 45 : 151 - 156