An Appearance of Mixed Large-cell Neuroendocrine Carcinoma and Hepatoid Carcinoma of Colon
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Published:
Jun 1, 2018
Keywords:
Large cell neuroendocrine carcinoma hepatoid adenocarcinoma alpha-fetoprotein
Main Article Content
Abstract
We present the first case of large-cell neuroendocrine carcinoma of the colon that combined with hepatoid adenocarcinoma without evidence of inflammatory bowel disease. The patient came to hospital to check up without any clinical symptoms. High serum alpha-fetoprotein (AFP) was found in this case. A clinician should realize that this rare tumor could be found in patient with intestinal mass along with high AFP level. Early diagnosis may improve outcome in this aggressive behavior and poor prognosis.
Article Details
How to Cite
Chavanisakun, C., & Tangjigamol, S. (2018). An Appearance of Mixed Large-cell Neuroendocrine Carcinoma and Hepatoid Carcinoma of Colon. Vajira Medical Journal : Journal of Urban Medicine, 62(3), 251–256. Retrieved from https://he02.tci-thaijo.org/index.php/VMED/article/view/195304
Section
Case Report
References
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14. Jung JY, Kim YJ, Kim HM, Kim HJ, Park SW, Song SY, et al. Hepatoid Carcinoma of the Pancreas Combined with Neuroendocrine Carcinoma. Gut and Liver. 2010; 4(1): 98-102
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16. Yoshihara T, Shinzaki S, Hiyama S. Metastatic colon neuroendocrine carcinoma found in a patient with ulcerative colitis during annual endoscopic surveillance. Gastrointest Endosc.2016; 84: 1075–6.
17. Travis WD, Linnoila RI, Tsokos MG, Hitchcock CL, Cutler GB Jr, Nieman L, et al. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow low cytometric study of 35 cases. Am J Surg Pathol. 1991; 15: 529-53.
18. Bourreille J, Metayer P, Sauger F. Existence of alpha feto protein during gastric-origin secondary cancer of the liver. La Presse Medicale. 1970; 78: 1277–8.
19. Su JS, Chen YT, Wang RC. Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma: a literature review. World J Gastroenterol. 2013; 19: 321–7
2. Grassia R, Bodini P, Dizioli P. Neuroendocrine carcinomas arising in ulcerative colitis: coincidences or possible correlations? World J Gastroenterol. 2009; 15: 4193–5.
3. Minocha V, Shuja S, Ali R. Large cell neuroendocrine carcinoma of the rectum presenting with extensive metastatic disease. Case Rep Oncol Med. 2014; 2014: 1–5.
4. Bernick PE, Klimstra DS, Shia J. Neuroendocrine carcinomas of the colon and rectum. Dis Colon Rectum. 2004; 47: 163–9.
5. Anagnostopoulos GK, Arvanitidis 0, Sakorafas G, Pavlakis G, Kolilekas L, Arkoumani E et al. Combined carcinoid-adenocarcinoma tumour of the anal canal. Scand J Gastroenterol. 2004;39: 198-200.
6. Hock YL, Scott KW, Grace RH. Mixed adenocarcinoma/carcinoid tumour of large bowel in a patient with Crohn's disease. J Clin Pathol. 1993; 46: 183-5.
7. Jiao YF, Nakamura S, Arai T, Sugai T, Uesugi N, Habano W et al. Adenoma, adenocarcinoma and mixed carcinoid-adenocarcinoma arising in a small lesion of the colon. Pathol Int. 2003;53: 457-62.
8. Knight BK, Hayes MM. Mixed adenocarcinoma and carcinoid tumour of the colon. A report of 4 cases with postulates on histogenesis. SAfr Med J. 1987; 72: 708-10.
9. Klimstra DS, Arnold R, Capella C, Kloppel G, Komminoth P, Solcia E, Rindi G. Neuroendocrine neoplasms of the colon and rectum. In: Bosman FT, Carneiro F, Hruban RH, Theise ND. WHO Classification of Tumours of the Digestive System. 4th Edition. France: The International Agency for Research on Cancer (IARC); 2010. p.174-7
10. Borgonovo G, Razzetta F, Assalino M, et al. Rectal hepatoid carcinoma with liver metastases in a patient affected by ulcerative colitis. Hepatobiliary Pancreat Dis Int. 2008; 7: 539–43.
11. Liu Q, Bannan M, Melamed J. Two cases of hepatoid adenocarcinoma of the intestine in association with inflammatory bowel disease. Histopathology. 2007; 51: 123–5.
12. Lattes C, Carella R, Faggioli S. Hepatoid adenocarcinoma of the rectum arising in ulcerative colitis: report of a case. Dis Colon Rectum. 2000; 43: 105–8.
13. Armaghani A, Gonzalo DH, Daily K. Hepatoid adenocarcinoma of the colon. BMJ Case Rep. 2015; 2015: bcr2014206222.
14. Jung JY, Kim YJ, Kim HM, Kim HJ, Park SW, Song SY, et al. Hepatoid Carcinoma of the Pancreas Combined with Neuroendocrine Carcinoma. Gut and Liver. 2010; 4(1): 98-102
15. Park JS, Kim L, Kim CH, Bang BW, Lee DH, Jeong S, et al. Synchronous large-cell neuroendocrine carcinoma and adenocarcinoma of the colon. Gut Liver. 2010; 4: 122-5.
16. Yoshihara T, Shinzaki S, Hiyama S. Metastatic colon neuroendocrine carcinoma found in a patient with ulcerative colitis during annual endoscopic surveillance. Gastrointest Endosc.2016; 84: 1075–6.
17. Travis WD, Linnoila RI, Tsokos MG, Hitchcock CL, Cutler GB Jr, Nieman L, et al. Neuroendocrine tumors of the lung with proposed criteria for large-cell neuroendocrine carcinoma. An ultrastructural, immunohistochemical, and flow low cytometric study of 35 cases. Am J Surg Pathol. 1991; 15: 529-53.
18. Bourreille J, Metayer P, Sauger F. Existence of alpha feto protein during gastric-origin secondary cancer of the liver. La Presse Medicale. 1970; 78: 1277–8.
19. Su JS, Chen YT, Wang RC. Clinicopathological characteristics in the differential diagnosis of hepatoid adenocarcinoma: a literature review. World J Gastroenterol. 2013; 19: 321–7