Solitary Fibrous Tumor of the Pancreas: A Case Report and Review Literature
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Published:
Jun 1, 2018
Keywords:
Solitary fibrous tumor pancreas mesenchymal tumor
Main Article Content
Abstract
Solitary fibrous tumor represents a single spectrum of mesenchymal tumors with fibroblastic differentiation. The pleura is the first organ that tumors originate and occur most commonly in the thoracic cavity. Solitary fibrous tumor of pancreas is extremely rare and slow growing with asymptomatic. We report the case of a patient with a primary solitary fibrous tumor of the pancreas with a review of the literature. This case is a 56-year-old woman, presented with right upper abdominal pain for 1 month. Whole abdominal CT scan revealed a well-defined hypervascular mass at right upper abdominal region, sized 6.3x5.9x5.7 cm, abutting duodenum and pancreas. The gross specimen displayed a well circumscribed solid mass at pancreatic head, measuring 7.5x6.5x6.5cm. On histomorphology, the mass comprises bland-looking spindle cell neoplasm. Immunohistochemical studies showed positive vimentin, Bcl-2, CD99, CD34 and STAT-6 compatible with solitary fibrous tumor. The patient had been still alive 1 year after surgery.
Article Details
How to Cite
Puripat, N., & Tangjitgamol, S. (2018). Solitary Fibrous Tumor of the Pancreas: A Case Report and Review Literature. Vajira Medical Journal : Journal of Urban Medicine, 62(3), 257–266. Retrieved from https://he02.tci-thaijo.org/index.php/VMED/article/view/195308
Section
Case Report
References
1. Lüttges J, Mentzel T, Hübner G, Klöppel G. Solitary fibrous tumor of the pancreas: a new member of the small group of mesenchymal pancreatic tumors. Virchows Arch. 1999;435(1): 37-42.
2. Chatti K, Nouira K, Ben Reguigua M, Bedioui H, Oueslati S, et al. Solitary fibrous tumor of the pancreas. A case report. Gastroenterol Clin Biol. 2006;30(2):317-9.
3. Miyamoto H, Molena DA, Schoeniger LO, Xu H. Solitary Fibrous Tumor of the Pancreas: A Case Report. Int J Surg Pathol. 2007; 15(3): 311-4.
4. Chatti K, Nouira K, Ben Reguigua M, Bedioui H, Oueslati S, Laabidi B et al. Solitary fibrous tumor of the pancreas. A case report. Gastroenterol Clin Biol. 2006; 30:317–9.
5. Srinivasan VD, Wayne JD, Rao MS, Zynger D. Solitary Fibrous Tumor of the Pancreas: Case Report with Cytologic and Surgical Pathology Correlation and Review of the Literature. J Pancreas. 2008; 9(4):526-30.
6. Kwon HJ, Byun JH, Kang J, Park SH, Lee MG. Solitary Fibrous Tumor of the Pancreas: Imaging Findings. Korean J Radiol. 2008; 9: 48-51.
7. Chetty R, Jain R, Serra S. Solitary fibrous tumor of the pancreas. Ann Diagn Pathol. 2009; 13:339–43.
8. Ishiwatari H, Hayashi T, Yoshida M, Kuroiwa G, Sato Y, et al. A case of solitary fibrous tumor of the pancreas. Nihon Shokakibyo Gakkai Zasshi. 2009; 106(7):1078-85.
9. Sugawara, Y., Sakai, S., Aono, S. Solitary fibrous tumor of the pancreas. Jpn J Radiol. 2010; 28(6):479-82.
10. Tasdemir A, Soyuer I, Yurci A, Karahanli I, Akyildiz H. A Huge Solitary Fibrous Tumor Localized in the Pancreas: A Young Women. JOP. J Pancreas. 2012; 13(3):304-7.
11. Santos IAM, Santos VM, Oliveira OCG, De Marco M. Solitary fibrous tumour of the pancreas: a case report. An. Sist. Sanit. Navar. 2012; 35 (1):133-6.
12. Hwang JD, Kim JW, Chang JC. Imaging findings of a solitary fibrous tumor in pancreas: a case report. J Korean Soc Radiol. 2014; 70:53–7.
13. Baxter AR, Newman E, Hajdu CH. Solitary fibrous tumor of the pancreas. J Surg Case Rep. 2015; 12: 1–4.
14. Tanaka K, Kishimoto T, Ohtsuka M, Nakatani Y, Miyazaki M. Importance of NAB2-STAT6 Fusion in the Diagnosis of Pancreatic Solitary Fibrous Tumor with Hamartoma-Like Features: Case Rep Pathol. 2015;2015:149606
15. Spasevska L, Janevska V, Janevski V, Noveska B, Zhivadinovik J. Solitary fibrous tumor of the pancreas: A case report and review of the literature. Prilozi (Makedonska Akademija na Naukite i Umetnostite. Oddelenie za Medicinski Nauki). 2016; 37(2-3):115-20.
16. Paramythiotis D, Kofina K, Bangeas P, Tsiompanou F, Karayannopoulou G. Solitary fibrous tumor of the pancreas: Case report and review of the literature. World J Gastrointest Surg. 2016; 8(6): 461-6.
17. D’Amico F, Ruffolo C, Romano M, Domenico MD, Sbaraglia M. Rare Neoplasm Mimicking Neuoroendocrine Pancreatic Tumor: A Case Report of Solitary Fibrous Tumor with Review of the Literature. Anticancer Res. 2017; 37:3093-7.
18. Sheng Q, Xu W, Liu J, Shen B, Deng X. Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature. Onco Targets Ther. 2017; 10: 1853-8.
19. Kim JY, Song JS, Park H. Primary mesenchymal tumors of the pancreas single-center experience over 16 years. Pancreas. 2014; 43(6):959-68.
20. Fletcher CDM, Bridge J.A, Lee JC. Extrapulmonary solitary fibrous tumor. In: Fletcher C.D.M., Bridge J.A., Hogendoorn P.C.W., Mertens F, editors. WHO classification of tumors of soft tissue and bone. 4thed. Lyon Cedex, France: International Agency for Research on cancer; 2013.p. 80-2.
21. Daigeler A, Lehnhardt M, Langer S, Steinstraesser L, Steinau HU, et al. Clinicopathological findings in a case series of extrathoracic solitary fibrous tumors of the soft tissues. BMC Surgery. 2006; 6:10.
22. Wignall OJ, Moskovic EC, Thway K, Thomas JM. Solitary fibrous tumors of the soft tissues: Review of the imaging and clinical features with histopathologic correlation. AJR. 2010; 195:55–62.
23. Wang H, Chen P, Zhao W, Shi L, Gu X, Xu Q. Clinicopathological findings in a case series of abdominopelvic solitary fibrous tumors. Oncol Lett. 2014; 7(4): 1067–72.
24. Penel N, Yaovi Amela E, Decanter G, Robin YM, Marec-Berard P. Solitary fibrous tumors and so-called hemangiopericytoma Sarcoma.2012;2012:690251.
25. Fukunaga M, Naganuma H, Ushigome S. malignant solitary fibrous tumor of peritoneum. Histopathology. 1996; 28: 463-6.
26. Hasegawa T, Matsuno Y, Shimoda T. Extrathoracic solitary fibrous tumor; their histological variability and potentially aggressive behavior. Hum pathol 1999; 3: 1464-73.
27. Vallat-Decouvelaere AV, Dry SM, Fletcher CD. Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intrathoracic tumor. Am J Surg Pathol. 1998; 22: 1501-1.
28. Sun Y, Naito Z, İshiwata T, Maeda S, Sugisaki Y, Asano G. Basic FGF and Ki-67 proteins useful for immunohistological diagnostic evaluations in malignant solitary fibrous tumor. Pathol Int. 2003; 53:284-90.
29. Ganly I, Patel SG, Stambuk HF, Coleman M, Ghossein R, Carlson D, et al. Solitary Fibrous Tumors of the Head and Neck. Arch Otolaryngol Head Neck Surg. 2006; 132:517-25.
30. Daigeler A, Lehnhard M, Langer S, Steinstraesser L, Steinau HU, Mentzel T et al. Clinicopathological findings in a case series of extrathoracic solitary fibrous tumors of soft tissues. BMC Surgery. 2006; 6:10:
31. Wei YC, Li CF, Sung MT, Chen YT, Ko SF, Eng HL, et al. Primary myxoid solitary fibrous tumor involving the seminal vesicle. Pathol Int. 2006; 56:642-4.
32. Geramizadeh B, Marzban M, Churg A. Role of immunohistochemistry in the diagnosis of solitary fibrous tumor, a review. Iran J Pathol. 2016; 11(3): 195–203.
2. Chatti K, Nouira K, Ben Reguigua M, Bedioui H, Oueslati S, et al. Solitary fibrous tumor of the pancreas. A case report. Gastroenterol Clin Biol. 2006;30(2):317-9.
3. Miyamoto H, Molena DA, Schoeniger LO, Xu H. Solitary Fibrous Tumor of the Pancreas: A Case Report. Int J Surg Pathol. 2007; 15(3): 311-4.
4. Chatti K, Nouira K, Ben Reguigua M, Bedioui H, Oueslati S, Laabidi B et al. Solitary fibrous tumor of the pancreas. A case report. Gastroenterol Clin Biol. 2006; 30:317–9.
5. Srinivasan VD, Wayne JD, Rao MS, Zynger D. Solitary Fibrous Tumor of the Pancreas: Case Report with Cytologic and Surgical Pathology Correlation and Review of the Literature. J Pancreas. 2008; 9(4):526-30.
6. Kwon HJ, Byun JH, Kang J, Park SH, Lee MG. Solitary Fibrous Tumor of the Pancreas: Imaging Findings. Korean J Radiol. 2008; 9: 48-51.
7. Chetty R, Jain R, Serra S. Solitary fibrous tumor of the pancreas. Ann Diagn Pathol. 2009; 13:339–43.
8. Ishiwatari H, Hayashi T, Yoshida M, Kuroiwa G, Sato Y, et al. A case of solitary fibrous tumor of the pancreas. Nihon Shokakibyo Gakkai Zasshi. 2009; 106(7):1078-85.
9. Sugawara, Y., Sakai, S., Aono, S. Solitary fibrous tumor of the pancreas. Jpn J Radiol. 2010; 28(6):479-82.
10. Tasdemir A, Soyuer I, Yurci A, Karahanli I, Akyildiz H. A Huge Solitary Fibrous Tumor Localized in the Pancreas: A Young Women. JOP. J Pancreas. 2012; 13(3):304-7.
11. Santos IAM, Santos VM, Oliveira OCG, De Marco M. Solitary fibrous tumour of the pancreas: a case report. An. Sist. Sanit. Navar. 2012; 35 (1):133-6.
12. Hwang JD, Kim JW, Chang JC. Imaging findings of a solitary fibrous tumor in pancreas: a case report. J Korean Soc Radiol. 2014; 70:53–7.
13. Baxter AR, Newman E, Hajdu CH. Solitary fibrous tumor of the pancreas. J Surg Case Rep. 2015; 12: 1–4.
14. Tanaka K, Kishimoto T, Ohtsuka M, Nakatani Y, Miyazaki M. Importance of NAB2-STAT6 Fusion in the Diagnosis of Pancreatic Solitary Fibrous Tumor with Hamartoma-Like Features: Case Rep Pathol. 2015;2015:149606
15. Spasevska L, Janevska V, Janevski V, Noveska B, Zhivadinovik J. Solitary fibrous tumor of the pancreas: A case report and review of the literature. Prilozi (Makedonska Akademija na Naukite i Umetnostite. Oddelenie za Medicinski Nauki). 2016; 37(2-3):115-20.
16. Paramythiotis D, Kofina K, Bangeas P, Tsiompanou F, Karayannopoulou G. Solitary fibrous tumor of the pancreas: Case report and review of the literature. World J Gastrointest Surg. 2016; 8(6): 461-6.
17. D’Amico F, Ruffolo C, Romano M, Domenico MD, Sbaraglia M. Rare Neoplasm Mimicking Neuoroendocrine Pancreatic Tumor: A Case Report of Solitary Fibrous Tumor with Review of the Literature. Anticancer Res. 2017; 37:3093-7.
18. Sheng Q, Xu W, Liu J, Shen B, Deng X. Pancreatic solitary fibrous tumor in a toddler managed by pancreaticoduodenectomy: a case report and review of the literature. Onco Targets Ther. 2017; 10: 1853-8.
19. Kim JY, Song JS, Park H. Primary mesenchymal tumors of the pancreas single-center experience over 16 years. Pancreas. 2014; 43(6):959-68.
20. Fletcher CDM, Bridge J.A, Lee JC. Extrapulmonary solitary fibrous tumor. In: Fletcher C.D.M., Bridge J.A., Hogendoorn P.C.W., Mertens F, editors. WHO classification of tumors of soft tissue and bone. 4thed. Lyon Cedex, France: International Agency for Research on cancer; 2013.p. 80-2.
21. Daigeler A, Lehnhardt M, Langer S, Steinstraesser L, Steinau HU, et al. Clinicopathological findings in a case series of extrathoracic solitary fibrous tumors of the soft tissues. BMC Surgery. 2006; 6:10.
22. Wignall OJ, Moskovic EC, Thway K, Thomas JM. Solitary fibrous tumors of the soft tissues: Review of the imaging and clinical features with histopathologic correlation. AJR. 2010; 195:55–62.
23. Wang H, Chen P, Zhao W, Shi L, Gu X, Xu Q. Clinicopathological findings in a case series of abdominopelvic solitary fibrous tumors. Oncol Lett. 2014; 7(4): 1067–72.
24. Penel N, Yaovi Amela E, Decanter G, Robin YM, Marec-Berard P. Solitary fibrous tumors and so-called hemangiopericytoma Sarcoma.2012;2012:690251.
25. Fukunaga M, Naganuma H, Ushigome S. malignant solitary fibrous tumor of peritoneum. Histopathology. 1996; 28: 463-6.
26. Hasegawa T, Matsuno Y, Shimoda T. Extrathoracic solitary fibrous tumor; their histological variability and potentially aggressive behavior. Hum pathol 1999; 3: 1464-73.
27. Vallat-Decouvelaere AV, Dry SM, Fletcher CD. Atypical and malignant solitary fibrous tumors in extrathoracic locations: evidence of their comparability to intrathoracic tumor. Am J Surg Pathol. 1998; 22: 1501-1.
28. Sun Y, Naito Z, İshiwata T, Maeda S, Sugisaki Y, Asano G. Basic FGF and Ki-67 proteins useful for immunohistological diagnostic evaluations in malignant solitary fibrous tumor. Pathol Int. 2003; 53:284-90.
29. Ganly I, Patel SG, Stambuk HF, Coleman M, Ghossein R, Carlson D, et al. Solitary Fibrous Tumors of the Head and Neck. Arch Otolaryngol Head Neck Surg. 2006; 132:517-25.
30. Daigeler A, Lehnhard M, Langer S, Steinstraesser L, Steinau HU, Mentzel T et al. Clinicopathological findings in a case series of extrathoracic solitary fibrous tumors of soft tissues. BMC Surgery. 2006; 6:10:
31. Wei YC, Li CF, Sung MT, Chen YT, Ko SF, Eng HL, et al. Primary myxoid solitary fibrous tumor involving the seminal vesicle. Pathol Int. 2006; 56:642-4.
32. Geramizadeh B, Marzban M, Churg A. Role of immunohistochemistry in the diagnosis of solitary fibrous tumor, a review. Iran J Pathol. 2016; 11(3): 195–203.