The Relationship of One Abnormal 100 Grams OGTT Value and Large for Gestational Age Newborn

Abstract

The Relationship of One Abnormal 100 Grams OGTT Value and Large for Gestational Age Newborn

Chantawat      Sheanakul,     MD

Department of Obstetrics and Gynecology, BMA Medical College and Vajira Hospital

Objective: To study the incidence of large for gestational age newborn of mothers with abnormal one value 100 grams oral glucose tolerance test (100 grams OGTT) compared to those of mothers with normal value 100 grams OGTT

Study design: Historical cohort study.

Subjects: Ninety six pregnant women attending at antenatal care unit in BMA Medical College and Vajira Hospital from April 1996 - March 1999 with certain gestational age and risk for gestational diabetes mellitus, who underwent 100 grams OGTT test at 24-28 weeks gestational age.

Methods: The medical records of pregnant women at risk for gestational diabetes mellitus who came for antenatal care and underwent OGTT between April 1996 to March 1999 were reviewed.  The subjects were divided into 2 groups, 48 women in each group.  The study group was pregnant women with abnormal one value 100 grams OGTT. The control group was ones with normal 100 grams OGTT.  The incidence rates of large for gestational age newborn between two groups were compared.

Main outcome measures: Incidence of large for gestational age newborn.

Results: Incidence of large for gestational age newborn born from mothers in the study group (24.44%) was significantly higher than in the control group (6.66%).

Conclusion: Pregnant women who had one abnormal value of 100 grams OGTT had higher risk of having large for gestational age newborn than those with all normal values of 100 grams OGTT. The obstetrician should be careful in taking care of these particular group of patients and repeat the test again.

Key word: diabetes mellitus, OGTT, pregnancy

Vajira Med J 2003 ; 47 : 1 - 8