Prevalence of Vertical Transmission of HIV at Faculty of Medicine Vajira Hospital

Main Article Content

Jutatip Thamwinitchai
Taweewong Tantracheewathorn

Abstract

Objective: To study the prevalence of vertical transmission of HIV at Faculty of Medicine Vajira Hospital.


Methods: Data from medical records of children born from an HIV-infected mother at Faculty of Medicine Vajira Hospital, Navamindradhiraj University from December 1st, 2010 to December 31st, 2018 were collected as a retrospective descriptive study.


Results: One hundred and forty-three cases were recruited. The average gestational age of the infants was 38.1 ± 1.7 weeks (31.9-42.0), and mean birth weight was 2,830.0 ± 454.3 grams (1,480-4,000). Seventy five cases (52.4%) were male and 68 cases (47.6%) were female. Ninety-seven (67.8%) and 46 (32.2%) children were categorized into standard risk group and high risk group, respectively. The most common complications were early onset neonatal sepsis (17.5%), neonatal jaundice (2.8%) and pneumonia (2.1%). All infants were cure and average hospital length of stay was 6.3 ± 6.3 days (2-45). Only one infant (0.7%) from irregular antiretroviral drugs intake mother was infected. This neonate received only zidovudine (AZT) for 4 weeks after birth because his mother gave history of regular antiretroviral drugs intake for more than 12 weeks before delivery.


Conclusion: The prevalence of vertical transmission of HIV at Faculty of Medicine Vajira Hospital was 0.7%. The infected baby born from high risk mother received only AZT after birth for preventing HIV vertical transmission.

Downloads

Download data is not yet available.

Article Details

Section
Original Articles

References

World Health Organization. Antiretroviral drugs for treating pregnant women and preventing HIV infection in infants, 2010. Recommendations for a public health approach. Geneva, Switzerland:WHO, 2010.

Lolekha R, Boonsuk S, Plipat T, Martin M, Tonputsu C, Punsuwan N, et al. Elimination of mother-to-child transmission of HIV-Thailand. MMWR Morb Mortal Wkly Rep 2016;65(22):562-6.

Lolekha R, Chokephaibulkit K, Phanuphak N, Chaithongwongwatthana S, Kietiburanakul S, Chetchotisakd P, et al. Thailand national guidelines for the prevention of mother-to-child transmission of HIV 2016. Asian Biomed 2017; 11(2):145-59.

Phanuphak N, Phanuphak P. History of the prevention of mother-to-child transmission of HIV inThailand. J Virus Erad 2016;2:107-9.

Ongwandee S, Kiertiburanakul S, Avihingsanon A. Thailand national guidelines on HIV/AIDS treatment and prevention 2017. Bangkok: The Agricultural Co-operative Federation of Thailand; 2017. p.29-32.

Dinh TH, Mushavi A, Shiraishi RW, Barr BT, Balachandra S, Shambira G, et al. Impact of timing of antiretroviral treatment and birth weight on mother-to-child human immunodeficiency virus transmission: Findings from an 18-month prospective cohort of a nationally representative sample of mother–infant pairs during the transition from option A to option B+ in Zimbabwe. Clin Infect Dis 2018;66(4):576-85.

Puthanakit T, Thepnarong N, Chaithongwongwatthana S, Anugulruengkitt S, Anunsittichai O, Theerawit T, et al. Intensification of antiretroviral treatment with raltegravir for pregnant women living with HIV at high risk of vertical transmission. J virus Eradication 2018;4:e1-6.

Tonpudsa C, Loleka R, Pavaputanondh P, Puthanakit T, Kosalaraksa P, Petdachai W, et al. Remaining causes of mother to child HIV transmission (MTCT) in Thailand: barriers to achieving <1% of MTCT rate. 9th IAS Conference on HIV Science;2017 July 23-26. Paris, France. Poster abstract No. A-854-0250-02238.

Saothong N, Yukhong T. Outcomes of antiretroviral drug usage for prevention of mother to child transmission at Maesai Hospital, Chiang Rai Province. Nurs Pub Health Educat J 2013;12-24.

Lauwahutanont S. Mother to child HIV transmission rate in Sena Hospital. J Prev Med 2013;3:55-61.

Limlikhit T. Mother to child HIV transmission rate in Detudom Crown Prince Hospital during Fiscal Year 2013-2016. Mahasarakham Hosp J 2016;13:11-21.

Mahy M, Penazzato M, Ciaranello A, Mofenson L, Yiannoutsos C, Davies MA, et al. Improving estimates of children living with HIV from the spectrum AIDS impact model. AIDS 2017; 31 Suppl 1:S13-22.

Manosuthi W, Ongwandee S, Bhakeecheep S, Leechawengwongs M, Ruxrungtham K, Phanuphak P, et al. Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents 2014, Thailand. AIDS Research and Therapy 2015;12:e12. doi: 10.1186/s12981-015-0053-z.

World Health Organization. WHO recommendations on the diagnosis of HIV infection in infants and children. Geneva, Switzerland: WHO, 2010.