Thai Scales for Outcomes in Parkinson’s Disease-Nighttime Sleep and Modified Parkinson’s Disease Sleep Scale for Assessment of Nighttime Sleep Disorder Compared with Pittsburgh Sleep Quality Index at the Faculty of Medicine Vajira Hospital
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Abstract
Objectives: This study aimed to evaluate the sensitivity and specificity of the Thai versions of Scales for Outcomes in Parkinson’s Disease-Nighttime Sleep (SCOPA-NS) and Modified Parkinson’s Disease Sleep Scale (MPDSS) test for patients with Parkinson’s disease in comparison with the Pittsburgh Sleep Quality Index (PSQI) test.
Methods: This cross-sectional study enrolled patients with Parkinson’s disease who sought treatment at the OPD department, Division of Neurology, Faculty of Medicine Vajira Hospital. The study was conducted from 1 March 2019 to 31 December 2019. Volunteers completed Thai SCOPA-NS and MPDSS sleep tests to obtain the sensitivity and specificity of each test, which was then compared with the PSQI test.
Results: Of the 216 volunteers, 200 met the study criteria. To evaluate nighttime sleep, SCOPA-NS test and MPDSS test in Thai language were used. The prevalence rates of sleep disorders in volunteers using the SCOPA-NS test and MPDSS test were 62.5% (95% confidence interval [CI] 55.4–69.2) and 52.5% (95% CI 45.3–59.6), respectively. Youden’s index (1− (sensitivity + specificity)) was used to find the optimal cut-off points by comparing it with the PSQI test. SCOPA-NS test has a sensitivity of 83.1% (95%CI 75.3–89.2), specificity of 71.1% (95% CI 59.5–80.9), positive predictive value (PPV) of 82.4% (95% CI 74.6–88.6), and negative predictive value (NPV) of 72% (95% CI 60.4–81.8), whereas the MPDSS test has a sensitivity of 71.8% (95% CI 63.0–79.5), specificity of 78.9% (95% CI 68.1 87.5), PPV of 84.8% (95% CI 76.4–91.0), and NPV of 63.2% (95% CI 52.6–72.8). The volunteers preferred doing the SCOPA-NS test than the MPDSS test with preference rates of 65.5% and 34.5%, respectively.
Conclusion: Thai SCOPA-NS test has higher sensitivity but lower specificity than the MPDSS test. However, patients significantly prefer doing the Thai SCOPA-NS test than the MPDSS test. Both tests can be used to evaluate patients with Parkinson’s disease at comparable accuracy. However, Thai SCOPA-NS test took shorter test, and patients with Parkinson’s disease prefer this test. We recommend using Thai SCOPA-NS in screening for sleep disorder in this patient population.
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References
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