Nutritional Status in Patients Hospitalized with Acute Exacerbation of COPD

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Sunisa Khamharn
Santi Silairatana

Abstract

Introduction: Malnutrition is a common comorbidity in COPD and associated with increased incidences of complications during hospitalization due to acute exacerbation (AE).


Outcome: Primary outcome was access nutritional status in COPD patients who were hospitalized due to AE. Secondary outcome was access associated between malnutrition and treatment outcomes (length of stay, hospital mortality and complications)


Sample: COPD patients who diagnosis COPD with AE and admit at Vajira Hospital, Navamindhradhiraj University from April 1, 2018 to February 28, 2019.


Method: Prospective cohort study in COPD patients who were hospitalized due to AE to determine prevalence and to compare outcomes between patients with and without malnutrition. The anthropometric indices and biochemical data were recorded for by using Multiparameter Nutritional Index(NI). Patients were classified into malnutrition(NI≥5) and non-malnutrition groups(NI<5) using a reference normal value from NHANES.


Result: We included 56 COPD patients, The prevalence of malnutrition was 82.1% (n=46). When comparison between malnutrition and no malnutrition group we found in malnutrition group has significant normal ideal body weight than no malnutrition group (p<0.001). And in no malnutrition group tends to has overweight up to 75%. In outcome of treatment no significant in length of stay. In malnutrition group has mean length of stay 12.72±9.90 day. And in no malnutrition group has mean length of stay 10.70±7.59 day (p = 0.548). COPD patients with malnutrition showed significantly more complications during hospitalization due to AE than those without malnutrition 89.1% and 60% respectively (p-value 0.044). The last we found in malnutrition group has mortality 13% when in no malnutrition group has mortality 0% but insignificant in statistic.


Conclusion: The prevalence of malnutrition in patients with COPD in Thailand is very high and is significantly associated with more complications during AE. Nutritional assessment and intervention in this group is very important and should be considered.

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References

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