Efficacy and Adverse Effects of Sodium Phosphate and Polyethylene Glycol When Used in Bowel Preparation prior to Colonoscopy among Patients Admitted at Vajira Hospital
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Abstract
Objective: Bowel preparation is an important process before colonoscopy. Sodium phosphate (NaP) and polyethylene glycol (PEG) are the drugs mainly used in bowel preparation at Vajira Hospital. Since NaP is an osmotic laxative, it may cause dehydration and electrolyte imbalance. Hence, PEG is commonly utilized in patients admitted to the hospital. The fragile patients need to admitted for bowel preparation for colonoscopy. Thus, the current study aimed to compare the efficacy of NaP and PEG and their effect on electrolyte levels in these patients.
Methods: Datas were collected from admitted patients who received either NaP or PEG for bowel preparation at Vajira Hospital from January 1, 2016, to December 31, 2016.
Results: NaP and PEG did not significantly differ in terms of efficacy. However, compared with PEG, NaP significantly increased serum Na levels (+1.737 mmol/L) and decreased serum K levels (-0.517 mmol/L). Nevertheless, there was no remarkable difference in the changes in serum Na and K levels based on clinical data.
Conclusion: Thus, NaP can be used with caution in bowel preparation among admitted patients as it has minimal side effects on electrolyte levels.
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