The Cut-Off Value of HbA1c for Prediabetes and Diabetes among Obese Children and Adolescents

Main Article Content

Thanyaros Sinsophonphap
Khansatit Thavornsawadi

Abstract

Objective: To determine the optimal cut-off value of HbA1C for prediction of prediabetes and diabetes among obese children and adolescents age 10–15 years at Faculty of Medicine Vajira Hospital.


Methods: A cross-sectional descriptive study has been performed in 230 participants between 10-15 years old who underwent an OGTT in 2015-2020. The diagnostic performance of HbA1c for prediabetes and diabetes was determined using the area under the Receiver operating characteristic curve.


Results: The prevalence of prediabetes and diabetes was 35.2% and 3.1%, respectively. The kappa coefficient for agreement between OGTT and HbA1c was 87.07%. The optimal HbA1c cut-off value were ≥ 5.5 (AUC, 0.565; a sensitivity of 65.4% and a specificity of 45.1%) for prediabetes and ≥ 6.6 (AUC, 0.644; a sensitivity of 42.9% and specificity of 99.1%) for diabetes.


Conclusion: HbA1c has low sensitivity and specificity for diagnose prediabetes. HbA1c has low sensitivity but high specificity for predicting diabetes in Thai children and adolescents.

Article Details

How to Cite
Sinsophonphap, T., & thavornsawadi, khansatit. (2022). The Cut-Off Value of HbA1c for Prediabetes and Diabetes among Obese Children and Adolescents. Vajira Medical Journal : Journal of Urban Medicine, 66(4), 299–310. https://doi.org/10.14456/vmj.2022.30
Section
Original Articles

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