Progression of Hormonal Male Contraception

Abstract

Progression of Hormonal Male Contraception

Chonticha Kaewanuchit BNs, MSc (Biopharmaceutical sciences)*

Chengchan Kaewanuchit BEng, MEng (Electricity)**

Areerut Kaewanuchit MD***

* Department of Applied Science, Faculty of Science and Technology, Phranakhon Si Ayutthaya Rajabhat University, Phranakhon Si Ayutthaya Province

** Faculty of Engineering, Eastern Asia University, Thanyaburi, Pathumthani

*** Phranakhon Si Ayutthaya Hostipal, Phranakhon Si Ayutthaya

The evolution of family-planning organizations had traditionally concentrated on female contraception. Condom and vasectomy were the only male contraception being used in the past decades. Lately, progression of hormonal male contraception has been developed and will be a new option of male contraception. Various forms of testosterone and progesterone have been studied as male contraception, i.e. testosterone enanthate, testosterone undecanoate, depot medroxyprogesterone acetate, nor-ethisterone enanthate, desogestrel or etonogestrel, either alone or in combination. Several clinical trials found that these hormonal contraceptions displayed promising efficacy. Recent studies focused on androgen either in implant or injection forms and long-acting testosterone esters in order to produce azoospermia. These developments contribute to a major progression in hormonal male contraception.

Key words: hormonal male contraception, androgen, testosterone, progesterone

Vajira Med J 2009 ; 54 : 103 - 108