Bacteriology and Antibiotics Usage in Patients with Diabetic Foot Infection

Abstract

Bacteriology and Antibiotics Usage in Patients with Diabetic Foot Infection

Waigoon Stapanavatr MD

Burapa Karnjanabatr MD

Department of Surgery, BMA Medical College and Vajira Hospital

Infection in diabetic foot is usually severe and is the most common cause of admission in diabetic patients. If surgical management is delayed, improper or missed diagnosis, risk of amputation will be high since nearly half of diabetic foot infection patients have peripheral arterial occlusive diseases. Patients with diabetic foot infection who need surgical intervention are usually infected with multiple organisms. Staphylococcus aureus is the common cause of infection in the United States of America, which is different from Asia. In Asia, bacteria in diabetic foot infection are usually response to simple antibiotics e.g. Proteus Mirabilis, Escherichia Coli, Klebsiella Pneumoniae, etc. Proper management for patients with diabetic foot infection consists of appropriate correction of arterial occlusion and combination antibiotics to cover gram positive, gram negative and anaerobic organisms. Erythromycin, Ciprofloxacin and Gentamicin have sensitivity to organisms in diabetic foot infection in South East Asia.

Keywords: diabetic foot, organisms, antibiotics

Vajira Med J 2010 ; 54 : 199-208