Effects And Safety Of Common Sign With Varicose Vein Of Leg By Kasalak Oil Formula At Kapchoeng Hospital, Surin Province

Authors

  • Nobpawan Banchuen Suan Sunandha Rajabhat University
  • Paiwan Kosisut Kapchoenge Hospital, Kapchoenge District, Surin Province
  • Worawun Kobkitngarm Kapchoenge Hospital, Kapchoenge District, Surin Province
  • Thavatchai Kamoltham Suan Sunandha Rajabhat University

Keywords:

Effect And Safety, Severity Level, Common Sign With Varicose Vein, Kasalak Oil Formula

Abstract

The objectives of study were to compare severity levels of common sign with varicose vein of leg before and after treatment by Kasalak oil formula and to study adverse drug effect. Sample group were 31 people; they had treated at department of Thai Traditional and Alternative Medicine Kapchoeng hospital, Surin province between Januarys – September 2018. Kasalak oil formula used 5 drops applied to varicose vein of leg with 3 times a day (morning-midday-evening). Data analysis used Paired sample T-test statistics. Clinical of blood vessel type were Telangiectasia 13 people (41.94%), Reticular vein 16 people (51.61%) and Varicose Vein 2 people (6.45%). Results before treatment found that the sample group were fatigue at mine level ( =1.16) pain, swelling, clamp, itching and numbness at none level ( =0.68, 0.58, 0.13, 0.36, 0.55, respectively). Results after treatment 4 weeks found that the sample group were fatigue at mine level ( =0.94) pain, swelling, clamp, itching and numbness at none level ( =0.45, 0.29, 0.07, 0.10, 0.48, respectively). The comparison of severity levels of common sign with varicose vein of legs between before treatment and after treatment 4 weeks, it was found that the samples group decrease itching swelling and pain statistically significant at 0.05 without adverse drug effect (100%). Important research summary was Kasalak oil formula applied to the varicose vein in legs until 4 weeks can relieve itching swelling and pain.

References

1. Ali Esmail Al-Snafi, (Prof Dr). Medical importance of Datura fastuosa (syn:Datura metel) and Datura stramonium - A review. IOSR Journal Of Pharmacy 2017; Volume 7 Issue 2 Version.1: 43-58
2. Ange Antoine Abena et al. Neuropsychopharmacological Effects of Leaves and Seeds Extracts of Datura fastuosa. Biotechnology 2004; Vol.3 Issue 23: 109-113.
3. Eberhard RABE and Felizitas PANNIER. What have we learned from the Bonn Vein Study?. PHLEBOLOGY 2006; Volume 13 Number 4: 188-194
4. F. Charles Brunicardi et.al. Schwartz’s PRINCIPAL OF SURGERY. 10thed. New York: McGraw Hill Medical 2015.
5. Feuangfoo F. and et.al. Chronic Venous Insufficiency in Occupational Medicine. Royal Thai Army Medical Journal 2017; Vol.70-2: 97-104
6. Françoise PITSCH. Results from detection surveys on chronic venous disease in Eastern Europe. PHLEBOLOGY 2010; Volume 17 Number 2: 95-98
7. Ganesh. S, Radha. R, Jayshree N. A Review on Phytochemical and Pharmacological status of Datura fastuosa Linn. International Journal of Multidisciplinary Research and Development 2015; Volume 2 Issue 4 : 602-605
8. Issaravanich S. Rungsihirunrat K. and Ruangrungsi N. Microscopic, Molecular and Scopolamine Content Evalutions of Datura Metel L. VAR. Metel and Datura Metel L. VAR. Fastuosa. [Internet]. 2012 [cited 2018 January 23].Chulapedia. Available from: https://bit.ly/2JULbNZ.
9. Kaewchoothong A. Preparation and quality control of Zingiber cassumunar extract with high-yielded anti-inflammatory active compounds [Thesis Master Degree of Science]. Songkla: Songkla University; 2009.
10. Kraivaphan N. Subject of Pharmacology for Medical Students : Lessons 3 Antimuscarinic drugs [Internet]. N.d. [cited 2018 November 7]. CMU medicine pharmacology. Available from: http://www.med.cmu.ac.th/dept/pharmaco/pharmacology/Lesson03/03.htm
11. Leekaew P. Datura metel L.: Poisonous Ornamental plants [Internet]. 2015 [cited 2018 November 7]. Mahidol University Faculty of pharmacy; Knowledge Articles. Available from: https://bit.ly/2VM6Mvm.
12. Leelaudomlipi S. and et.al. Preminary Report: Initial Experience of Endovascular Laser Therapy for Varicose Veins Due To Greater Saphenous Vein Incompetence in Thailand. J Med Assoc Thai; Vol. 88 No.4: 473-477
13. Loathong N. and et.al. Varicose Vein treatment (Endo Venous Laser). Royal Thai Army Medical Journal 2007; Vol. 60 Supplement (1): 210-211
14. Michael A. Vasqze and Carolyn E. Munschauer. Venous Clinical Severity Score and quality-of-life assessment tools: application to vein practice. PHLEBOLOGY 2008; Volume 23: 259-275
15. Rajiv Mallick et.al. Treatment Patterns and Outcomes in Patients with Varicose Veins. American Health & Drug Benefits 2016; Volume 9 Number 8: 455-464
16. Ronald Melzack. The short-form McGill Pain Questionnaire. Elsevier Science Publishers B.V. 1987; Volume 30:191-197

Downloads

Published

2020-02-04

Issue

Section

Original Article