ASSOCIATION BETWEEN THE DURATION OF TYPE 2 DIABETES MELLITUS AND CHRONIC KIDNEY DISEASE IN KRANUAN DISTRICT, KHON KAEN PROVINCE.

Abstract

Chronic kidney disease is a major complication of diabetes. The main factor affecting the incidence of chronic kidney disease is the duration of having type 2 diabetes mellitus. Therefore, this study examined the association between the duration of having type 2 diabetes mellitus and chronic kidney disease in Kranuan District, Khon Kaen Province. This was an unmatched case-control. Data were collected from the medical records of 482 patients with type 2 diabetes mellitus at Somdet Phra Yupparaj Kranuan Hospital who received the service from 1 October 2019 to 30 September 2020. The experimental group consisted of 241 people with type 2 diabetes mellitus and chronic kidney disease. The control group consisted of 241 people with type 2 diabetes mellitus. They were selected by a simple sampling method. The association was analyzed by multiple logistic regression. The association size was presented by Adjusted Odds Ratio (OR_adj), 95% confidence interval.  The results indicated that when controlling for the effects of other variables, in the final equation, it was found that the duration of having type 2 diabetes mellitus was associated with the incidence of chronic kidney disease with statistical significance (p-value <0.05). The patients with type 2 diabetes with a duration of illness of 5 to 10 years and 10 years or more were 1.94 times and 3.48 times more likely to develop chronic kidney disease, respectively, compared to those with a long duration of illness less than 5 years. (OR_adj=1.94, 95%CI; 1.18-4.25), (OR_adj=3.48, 95%CI; 1.74-6.95), (p=0.001) Therefore, the guidelines for screening and controlling the complications of diabetes should be developed. The frequency of examining renal function, especially in the elderly people having diabetes for more than 5 years should also be increased.