Factors Related to Metformin Leftover Medicine in Patient with Type 2 Diabetes Mellitus in Roi-et Hospital, Muang District, Roi-et Province

Abstract

            The Metformin leftover is likely to increase. This research aimed to estimate the prevalence and to explore factors related to Metformin leftover medicine in Patient with Type 2 Diabetes Mellitus at Roi-Et Hospital, Muang District, Roi-Et Province. Method This study was cross-sectional analytical study. The samples were 400 patients with type 2 Diabetes Mellitus which registered in Diabetes Clinic Roi-Et Hospital during October 1, 2019 to September 30, 2020. examined the Metformin leftover in the Metformin drop box at diabetes clinic. Multiple logistic regression was used to associated between factors related to Metformin leftover medicine.

            Results The prevalence of patients who had Metformin leftover was 64.2%. Most patients (35.4%) had 1-10 pills left. About 63.4% of DM patients informed that the Metformin leftover because the doctor gave more medicine than number of days. The factors associated with Metformin Leftover were the DM patients aging >60 years old (OR_adj = 1.80, 95%CI = 1.11 – 2.91), the DM patients who had to taking ≥3 metformin tablets per day (OR_adj = 3.22, 95%CI = 1.85 – 5.62); and the patients whose doctor appointment in ≥3 months (OR_adj = 2.51, 95%CI = 1.60 – 3.96).

            In conclusion, the prevalence of patients who had Metformin leftover was quite high. Therefore, the appointment date and the number of Metformin tablet should be matched, Reduction of doctor appointment in ≤3 months, and Drug Administration in elderly patients.