Effect of mixing 2% lidocaine plus 0.5% bupivacaine versus 2% lidocaine in ultrasound-guided brachial block: a randomized study
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Abstract
Background: Brachial plexus nerve block with
local anesthetic has become the preferred technique
for arterio-venous bypass graft insertion for renal
dialysis because undesirable effect of general anesthesia
is avoided. Objectives: To determine difference in
duration of effect of adding 0.5% bupivacaine to
2% lidocaine comparing with 2% lidocaine with
adrenaline Methods: Double blinded, prospective,
randomized trial with thirty-nine end-stage renal
disease patients undergone arterio-ventricular access
surgery. Subjects were randomly allocated into
2 groups. Group L (21 subjects) to received 20 mL
of 2% lidocaine with 1:200000 adrenaline and
group BL (18 subjects) to received 5 mL of 0.5%
bupivacaine with 2% lidocaine with 1:200000
adrenaline to total volume of 20 mL. Results:
Duration of block represented by time to first analgesic
drug requested in group BL (5.7 + 3.5 hours) was
longer than group L (3.9 + 2.8 hours) with no statistical
significance (p=0.10). No statistical significant
difference between onset (time to start loss of
sensation), time-to-muscle-weakness, duration of
sensory and motor. Conclusions: Adding 0.5%
bupivacaine 5 mL to 2% lidocaine with 1:200000
adrenaline 15 mL to total dose of 20 mL for brachial
plexus block does not have any significant statistic
difference.
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