Preoxygenation with Oxygen-prefilled Anesthesia Breathing System Increased End Tidal Oxygen within Two Minutes: A Randomized Controlled Trial

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Khempet Sessumpun


Background: One minute deep breathing technique is a widely accepted method for preoxygenation, especially in emergency situations. This is usually performed without prefilling oxygen in the anesthesia breathing system. Thus, the patient does not receive 100% oxygen initially.
Objective: The aim of this study was to compare the efficacy of deep breathing preoxygenation technique between oxygen-prefilled system and non-prefilled system.
Methods: Randomized controlled trial study was conducted on 40 adults undergoing elective surgery. The patients were randomly assigned into 2 groups, oxygen-prefilled group and non-prefilled group.
Results: The mean end-tidal oxygen (EtO2) at the first minute in oxygen-prefilled group was significantly higher than non-prefilled group (77.85 ± 4.64% vs. 66.95 ± 6.61%; p < 0.001). There were 15 patients (75%) in prefilled group and 7 patients (35%) in non-prefilled group with EtO2 ≥ 85%
at 2 minute which are significantly difference (p < 0.001).
Conclusions: Preoxygenation with oxygen-prefilled is more efficient than non-prefilled anesthesia breathing system. However, it still provided suboptimal preoxygenation. So, extending the duration of deep breathing at least 2 minutes using oxygen-prefilled system is recommended.

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Original articles


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