Prolonged Apnea from Pseudocholinesterase Enzyme Deficiency in Emergency Cesarean Delivery under General Anesthesia: A Case Report
Keywords:
Cesarean section, General Anesthesia, Pseudocholinesterase, SuccinylcholineAbstract
We report a case of prolonged apnea in Chinese
parturient who received general anesthesia for emergency
cesarean section. A blood test confirmed she had
pseudocholinesterase enzyme deficiency leaded to
prolonged apnea and paralysis following administration of
succinylcholine. She regained adequate spontaneous
respiration after received mechanical ventilation for about
6 hours. Although pseudocholinesterase enzyme
deficiency is an uncommon condition, it may cause serious
outcomes in case that receive general anesthesia.
References
[Internet]. October 9, 2019. Available at: https://www.ncbi.
nlm.nih.gov/books/NBK470596/. Accessed Nov 20, 2019.
2. Cholinesterase Deficiency [Internet]. Available at: https://
accessanesthesiology.mhmedical.com/content.aspx?booki
d=852§ionid=49517388. Accessed Nov 20, 2019.
3. Zencirci B. Pseudocholinesterase enzyme deficiency: a case
series and review of the literature. Cases Journal 2009, 2:
9148 doi:10.1186/1757-1626-2-9148.
4. Pseudocholinesterase deficiency [Internet]. Available at:
https://rarediseases.info.nih.gov/diseases/7482/pseudocholinesterase-
deficiency. Accessed Nov 20, 2019.
5. Abdullayev R, Küçükebe ÖB, Kaya R, et al. Pseudocholinesterase
Enzyme Deficiency in Adıyaman City Area. Turk J
Anaesth Reanim 2015;43:381-6.
6. Somchai Amornyotin, Adul Raksamani. Low plasma
cholinesterase (pseudocholinesterase) and prolonged
apnea. Thai journal of Anesthesiology 2545;28(2):83-7.
[in Thai]
7. Robertson GS. Serum cholinesterase deficiency II:
pregnancy. Brit J Anaesth 1966; 38: 361-69.
8. Cholinesterase–blood U.S. National Library of Medicine
[Internet]. Available at: https://medlineplus.gov/ency/article/
003358.htm. Accessed Nov 20, 2019.
9. Reinaldo Trujillo; William P. West, DO. Pseudocholinesterase
Deficiency StatPearls-NCBI Bookshelf [Internet]. June 4,
2019. Available at: https://www.ncbi.nlm.nih.gov/books/
NBK541032/.Accessed Nov 20, 2019.
Downloads
Published
How to Cite
Issue
Section
License
Copyright
Copyright of all articles published in the Thai Journal of Anesthesiology is held by the Thai Journal of Anesthesiology, the Royal College of Anesthesiologists of Thailand. Submission of a manuscript constitutes the authors' agreement that, upon acceptance for publication, copyright of the work is transferred to the Journal. The content and any opinions expressed in published articles are the sole responsibility of the authors and do not necessarily reflect the views of the editorial board or the Royal College of Anesthesiologists of Thailand.
Licensing
All articles are published open access under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND 4.0). Under this license, anyone may copy and redistribute published articles in any medium or format for non-commercial purposes, provided that appropriate credit is given to the authors and to the Thai Journal of Anesthesiology as the original source of publication, a link to the license is included, and the material is not modified in any way. Requests for commercial use or for adaptation of published material should be directed to the editorial office.
Authors' Rights
Although copyright is held by the Journal, authors retain the right to reuse their own published material in their future scholarly works, theses and dissertations, teaching, and academic presentations, and to deposit the final published version (PDF) in institutional or subject repositories or on personal and institutional websites, without embargo, provided that the Thai Journal of Anesthesiology is clearly acknowledged as the original place of publication.
