Prolonged Apnea from Pseudocholinesterase Enzyme Deficiency in Emergency Cesarean Delivery under General Anesthesia: A Case Report
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Published:
May 26, 2020
Keywords:
Cesarean section, General Anesthesia, Pseudocholinesterase, Succinylcholine
Main Article Content
Abstract
We report a case of prolonged apnea in Chinese
parturient who received general anesthesia for emergency
cesarean section. A blood test confirmed she had
pseudocholinesterase enzyme deficiency leaded to
prolonged apnea and paralysis following administration of
succinylcholine. She regained adequate spontaneous
respiration after received mechanical ventilation for about
6 hours. Although pseudocholinesterase enzyme
deficiency is an uncommon condition, it may cause serious
outcomes in case that receive general anesthesia.
Article Details
Section
Case reports
References
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[Internet]. October 9, 2019. Available at: https://www.ncbi.
nlm.nih.gov/books/NBK470596/. Accessed Nov 20, 2019.
2. Cholinesterase Deficiency [Internet]. Available at: https://
accessanesthesiology.mhmedical.com/content.aspx?booki
d=852§ionid=49517388. Accessed Nov 20, 2019.
3. Zencirci B. Pseudocholinesterase enzyme deficiency: a case
series and review of the literature. Cases Journal 2009, 2:
9148 doi:10.1186/1757-1626-2-9148.
4. Pseudocholinesterase deficiency [Internet]. Available at:
https://rarediseases.info.nih.gov/diseases/7482/pseudocholinesterase-
deficiency. Accessed Nov 20, 2019.
5. Abdullayev R, Küçükebe ÖB, Kaya R, et al. Pseudocholinesterase
Enzyme Deficiency in Adıyaman City Area. Turk J
Anaesth Reanim 2015;43:381-6.
6. Somchai Amornyotin, Adul Raksamani. Low plasma
cholinesterase (pseudocholinesterase) and prolonged
apnea. Thai journal of Anesthesiology 2545;28(2):83-7.
[in Thai]
7. Robertson GS. Serum cholinesterase deficiency II:
pregnancy. Brit J Anaesth 1966; 38: 361-69.
8. Cholinesterase–blood U.S. National Library of Medicine
[Internet]. Available at: https://medlineplus.gov/ency/article/
003358.htm. Accessed Nov 20, 2019.
9. Reinaldo Trujillo; William P. West, DO. Pseudocholinesterase
Deficiency StatPearls-NCBI Bookshelf [Internet]. June 4,
2019. Available at: https://www.ncbi.nlm.nih.gov/books/
NBK541032/.Accessed Nov 20, 2019.