Ultrasonographic Evaluation of Residual Gastric Volume after Ginger and Maltodextrin Ingestion: a Randomized, Crossover Trial in Volunteers

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Rattanaporn Burimsittichai
Natthaporn Tanpowpong
Wirinaree Kampitak
Nisarat Archawakom
Ladda Jullamusi


Background: An ingestion of clear fluid up to two hours before surgery has been accepted for patients undergoing elective procedures. Preoperative 12.5% maltodextrin has been administered to enhance patient recovery without reported adverse effects, however, there is still lack of well-defined impact on gastric residual volume (GRV) of different kinds of fluid. Objectives: To evaluate GRV measured by ultrasonography two hours after consuming ginger beverage compared to maltodextrin solution in healthy volunteers. Methods: Ten healthy volunteers, after an overnight fasting, ingested 400 ml of ginger and 12.5% maltodextrin in a randomized, crossover manner with one-week interval between ingestions. The antral cross-sectional area (CSA) was measured using ultrasonographic two-dimensional technique to evaluate GRV before and 2 hours after consumption of fluids. The primary outcome was predicted stomach volume calculated by validated model using antral CSA and age as variables. Secondary outcomes were side effects observed during the study. Results: The average fasting GRV was 1.0±0.5 ml/kg. Two hours after ingestion of ginger and maltodextrin, mean GRVs were 95.4±43.8 and 112.9±49.6 ml, respectively. There was no statistically significant difference in GRVs after ingestion of ginger and maltodextrin (mean difference ± standard error = -17.5±16.0 ml; 95%CI -48.8 to 13.9; P=0.307) and no participants had adverse effects. Conclusion: In healthy adults, the residual gastric volume, evaluated by ultrasonography, at two hours after ingestion of ginger beverage was not significantly different from 12.5% maltodextrin solution ingestion.

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