Comparison of Intravenous Tramadol 0.25 mg/kg and 0.5 mg/kg for Prevention of Shivering in Patients Undergoing Spinal Anesthesia
Keywords:
shivering, spinal anesthesia, tramadolAbstract
Background: Tramadol 0.5 mg/kg is the least effective dose for the prevention of shivering. No studies have been done on the dose of tramadol 0.25 mg/kg to prevent shivering. This study aims to compare the efficacy of intravenous tramadol 0.25 and 0.5 mg/kg for the prevention of shivering in patients who undergoing spinal anesthesia. Methods: A prospective, randomized, double-blind study was conducted. 86 patients who were scheduled for elective surgery under spinal anesthesia were randomly assigned to receive tramadol 0.25 mg/kg (group 1) and tramadol 0.5 mg/kg (group 2). After the patients received intrathecal injection of heavy bupivacaine anesthesia, their body temperature, blood pressure, and shivering level were measured using Crossley and Mahajan scale (The Shivering Classification). Results: The effectiveness in preventing shivering of group 1 and 2 were 81.4% and 86.0% (P= 0.559), with 18.6% of grade 3 or higher of shivering in group 1 and 14.0% in group 2 (P=0.502). The side effects in both groups were not different. Conclusion: The prevention of post-anesthetic shivering by use of 0.25 mg/kg and 0.5 mg/kg of tramadol has no different results and the side effects of the two groups of drugs were not different.
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