A Randomized Controlled Trial Comparing Ultrasound-Guided Genicular Nerve Block Combined with Acupuncture versus Acupuncture Alone for Patients with Knee Osteoarthritis
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Abstract
Background: Knee osteoarthritis (OA) is a prevalent cause of pain and disability, especially among the elderly. Standard treatments include pharmacological interventions and non-pharmacological methods like acupuncture. Combining genicular nerve block (GNB) with acupuncture may enhance pain relief and functional outcomes. This study compares the efficacy of GNB combined with acupuncture versus acupuncture alone in knee OA patients. Methods: A randomized controlled trial was conducted involving 82 participants with knee OA. Participants were randomized into two groups: 41 received GNB combined with acupuncture, and 41 received acupuncture alone. Pain was assessed using the visual analog scale (VAS), functional status with the Western Ontario and McMaster Universities Osteoarthritis Index (WOMAC), and quality of life with the 36-Item Short Form Health Survey questionnaire (SF-36). Assessments were conducted at baseline, and at weeks 2, 5, 10, and 12. Results: The GNB and acupuncture group experienced greater reductions in pain and WOMAC scores compared to the acupuncture group. By week 12, the GNB and acupuncture group reduced VAS scores from 5.45 to 1.80, while the acupuncture group showed a reduction from 5.92 to 2.50 (P < 0.05). WOMAC scores improved more significantly in the GNB and acupuncture group compared to the acupuncture group. Both groups reported high satisfaction, with no significant differences in quality of life. Conclusion: GNB combined with acupuncture offers superior pain relief and functional improvement compared to acupuncture alone in patients with knee OA, making it a promising non-surgical treatment option.
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