Packed Red Blood Cell Transfusion in Elective Coronary Artery bypass Graft Surgery in Siriraj Hospital

Authors

  • Chirawan Lawanwisut Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Kattiya Manomayangkul Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Sirilak Suksompong Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Benno von Bormann Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Nattawan Sirichuntakul Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Vanda Pattaratuma Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Punnarerk Thongjarearn Department of Anesthesiology, Faculty of Medicine, Siriraj Hospital, Mahidol University
  • Parichart Permpikul Department of Transfusion Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University

Abstract

Background: Coronary bypass graft surgery (CABGs) is considered to be an operation with high rate of packed red blood cell (PRBC) transfusion. The aim of this prospective obser - vational study is to evaluate the prevalence and risk factors of PRBC  transfusion in elective CABGs in Siriraj Hospital.

Study design and Method: Between November 2011 - September 2013, a prospective observational study was conducted and 300 patients undergoing isolated, first time CABG were enrolled. Patients’ preoperative variables and postoperative outcomes, as well as perioperative transfusion characteristics were recorded.

Results: A total of 300 patients were enrolled in the study. Overall, PRBC transfusion was utilized in 291 patients (97%). Two hundred and forty of these patients (80%) received PRBC more than 2 units. Univariate analysis identified female gender, age > 65 years, BMI < 30 kg/m2, NYHA class 3-4, diabetic mellitus, hypertension, preoperative hemoglobin concen-tration < 12 g/dl, and creatinine clearance < 60 ml/min as significant predictors of PRBC transfusion > 2 units. The result of multivariate analysis showed BMI < 30 kg/m2, NYHA class 3-4, diabetic mellitus and preoperative hemoglobin < 12 g/dl were significant predictors of PRBC transfusion > 2 units.

Conclusions: Transfusion rate for CABG patients in our institute is high. As BMI < 30 kg/m2, NYHA class ≥ 3, diabetic mellitus, and preoperative hemoglobin < 12 g/dl turned out to be the most significant predictors of red cell transfusion, almost all patients had at least one of these features.

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How to Cite

Lawanwisut, C., Manomayangkul, K., Suksompong, S., Bormann, B. von, Sirichuntakul, N., Pattaratuma, V., Thongjarearn, P., & Permpikul, P. (2016). Packed Red Blood Cell Transfusion in Elective Coronary Artery bypass Graft Surgery in Siriraj Hospital. Thai Journal of Anesthesiology, 40(4), 231–232. retrieved from https://he02.tci-thaijo.org/index.php/anesthai/article/view/58867

Issue

Vol. 40 No. 4 (2014): OCTOBER – DECEMBER

Section

Original articles

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