Fatigue and Health-related Quality of Life in School-age Children with Cancer Receiving Chemotherapy
Keywords:Fatigue, Health-related quality of live, school-age children with cancer
Health-related quality of life in school-age children with cancer receiving chemotherapy is an important aspect of demonstrating the effects of illness from cancer and chemotherapy on the lives of sick children. This descriptive correlational research studied health-related quality of life, and examined the correlation between fatigue and health-related quality of life in school- age children with cancer receiving chemotherapy. The concept of quality of life for health introduced by Ferrans and colleagues with the literature review was used as the study framework. Participants were children with cancer aged 8 to 12 years receiving chemotherapy in the outpatient department and pediatric ward at three tertiary hospitals, northern Thailand from November 2018 to April 2019. A total of 85 participants were selected. The research instruments included a demographic data form for parents, a demographic data form for sick children, the Multidimensional Fatigue Scale and a Health-related Quality of Life Questionnaire for School-age Children. Data were analyzed using descriptive statistics and Pearson’s correlation coefficient.
The results are as follows.
- Fifty-four point one percent of school-age children with cancer receiving chemotherapy had a moderate level of health-related quality of life (=65.48, SD=10.91).
- Sick children with low levels of fatigue will have a high level of health-related quality of life with statistical significance (r=.763, p<.001).
This study demonstrated that fatigue is an important factor correlated to perceived health-related quality of life in school-aged children with cancer receiving chemotherapy. These results provide a guideline for nursing planning to promote health-related quality of life in the target group and can also be used as a basis for further research.
Baggott, C. R., Dodd, M., Kennedy, C., Marina, N., Matthay, K. K., Cooper, B., & Miaskowski, C. (2011). An evaluation of the factors that affect the health-related quality of life of children following myelosuppressive chemotherapy. Supportive Care in Cancer, 19(3), 353-361.
Collins, J. J., Devine, T. D., Dick, G. S., Johnson, E. A., Kilham , H. A., Pinkerton, C. R., ...Portenoy, R.K. (2002). The measurement of symptoms in young children with cancer: The validation of the memorial symptom assessment scale in children aged 7-12. Journal of Pain and Symptom Management, 23(1), 10-16.
Erickson, J. M., Beck, S. L., Christian, B. R., Dudley, W., Hollen, P. J., Albritton, K. A., ... Godder, K. (2011). Fatigue, sleep-wake disturbances, and quality of life i n adolescents receiving chemotherapy. Journal of Pediatric Hematology/oncology, 33 (1), e17-e25. doi: 10.1097/MPH. 0b013e3181f46a46
Ferrans, C. E., Zerwic, J. J., Wilbur, J. E., & Larson, J. L. (2005). Conceptual model of health-related quality of life. Journal of Nursing Scholarship, 37 (4), 336-342.
Havighurst. R. J. (1972). Developmental tasks and education (3rd ed). David McKay Publications, United States.
Hockenberry-Eaton, M., Hinds, P., Howard, V., Gattuso, J., O'Neill, J. B., Alcoser, P., ...Euell, K. (1999). Developing a conceptual model for fatigue in children. European Journal of Oncology Nurs -ing, 3 (1), 5-11.
Hockenberry, M. J., Hooke, M. C., McCarthy, K., & Gregurich, (2011). Sickness behavior clustering in children with cancer. Journal of Pediatric Oncology Nursing, 28, 263-272.
Imsamran, W., Chaiwarawattana, A., Wiangnon, S., & Pongnikorn, D. (2015). Cancer in Thailand. National Cancer Institute, 8, 1-88.
Khananthana, K., Chermkum, S., & Triwanich, A. (2005). Adverse symptoms and management of children with acute leukemia during treatment with chemotherapy. Journal of Nursing and Health Care, 23 (2), 17-27. (In Thai)
Kunsu, P. (2001). Dementia in children with leukemia during chemotherapy. (Master of Nursing
Thesis Department of Pediatric Nursing). Graduate School, Chiang Mai University.
Langeveld, N., Ubbink, M., & Smets, E. (2000). “I don’t have any energy”: the experience of fatigue in young adult survivors of childhood cancer. European Journal of Oncology Nursing, 4 (1), 20-28. doi: 10.1054/ejon.1999.0063
Momani, T. E. G., Hathaway, D. K., & Mandrell, B. N. (2016). Factors affecting health-related Quality of life in children undergoing curative treatment for cancer: a review of the literature. Journal of Pediatric Oncology Nursing, 33(3), 228-240. doi: 10.1177/1043454215609585
O'Leary, M., Krailo, M., Anderson, J. R., & Reaman, G. H. (2008) . Progress in childhood cancer: 50 years of research collaboration, a report from the children 's oncology group. In Seminars in Oncology, 35, (5), 484-493. doi: 10.1053/j.seminoncol.2008.07.008
Pakkasama, S. (2016). Leukemia in children. Bangkok: Faculty of Medicine Ramathibodi Hospital Mahidol University. (In Thai)
Pan, H. T., Wu, L. M., & Wen, S. H. (2017). Quality of life and its predictors among children and adolescents with cancer. Cancer Nursing, 40 (5), 343-351. doi: 10.1097/NCC.0000000000 000433
Panmetharit, B., Phuttharat, U., & Wattanasit, P. (2008). Quality of life and factors influencing the quality of life of cancer patients in the southern region. Songklanagarind Medical Journal, 26 (5), 501-511. (In Thai)
Piaget, J. (1973). The child and reality. New York: Grossman publishers.
Polit, D. F. (2010). Statistis and analysis for nursing research (2 nd ed.). United States of America: Pearson Education.
Prajimtis, N. (2004). Symptom experience and fatigue management in children with leukemia who received chemotherapy. (Master of Nursing Thesis Department of Pediatric Nursing). Graduate Studies, Mahidol University. (In Thai)
Preechapongmit, K., Lamchang, S., & Jintrawet, U. (2012). Factors related to caregiving burden among caregivers of children with Asthma. Nursing Journal, 39 (4), 13-22. (In Thai)
Rompipat, S., Patoomwan, A., & Hanprasitkam, K. (2013). Predicting Factors of Fatigue in Children ReceivingChemotherapyforAcute Lymphoblastic Leukemia. Journal of Science and Technology, 21 (7), 595-608.
Sakthong, P. (2011). Health-related Quality of Life. Bangkok: Chulalongkorn University's publisher.(In Thai)
Kraiphibun, P. (2010). Cancer in children. Nonthaburi: Amarin Health. (In Thai)
Salas, M., Gabaldón, O., José Luis ,M., & Arce, M. (2004). Evaluation control symptom of oncology pediatric. Psicooncologia, 1, 231-250.
Shankar, S., Robison, L., Jenney, M. E., Rockwood, T. H., Wu, E., Feusner, J., ...Bhatia, S. (2005). Health-related quality of life in young survivors of childhood cancer using the Minneapolis-Manchester Quality of Life-Youth Form. Pediatrics, 115(2), 435-442. doi: 10.1542/peds. 2004-0649
Siripool, P. (2011). Symptom management: Nursing of pediatric patients with leukemia. Khon Kaen: Faculty of Nursing, Khon Kaen University. (In Thai)
Sitaresmi, M. N., Mostert, S., Gundy, C. M., & Veerman, A. J. (2008). Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia. Health and Quality of Life Outcomes, 6(1), 96. doi: 10.1186/1477-7525-6-96.
Srisathitnarakur, B. (2007). Sampling. Research methodology in nursing science (4 th edition, page 180-207). Bangkok: U&I Inter Media. (In Thai)
Srithipsukho, P. (2012). Quality of life for health of children with chronic diseases at Thammasat University Hospital. Journal of the Medical Association of Thailand, 95 (1), S8-S12. (In Thai)
Strategy and Planning Division Office of the Permanent Secretary for Public Health. (2016). Public Health Statistics 2016. Nontaburi: Strategy and Planning Division Ministry of Public Health. (In Thai)
Uttama, J., Kanthawang, S., & Meesukkho, J. (2016). Effects of Educational Program on Nurses’ Knowledge and Self-Efficacy in Caring for Leukemic Children with Chemotherapy Induced Fatigue. Nursing Journal, 43 (3), 1-12.
Varni, J. W., Seid, M., & Kurtin, P. S. (2001). PedsQL™ 4.0: reliability and validity of the Pediatric Quality of Life Inventory™ Version 4.0 Generic Core Scales in healthy and patient populations. Medical Care, 39(8), 800-812.
Wilson, I. B., & Cleary, P. D. (1995). Linking clinical variables with health-related quality of life: a conceptual model of patient outcomes. JAMA, 273(1), 59-65.
Zareifar, S., Farahmandfar, M. R., Cohan, N., Modarresnia, F., & Haghpanah, S. (2012). Evaluation of health related quality of life in 6–18 years old patients with acute leukemia during chemotherapy. The Indian Journal of Pediatrics, 79(2), 177-182. doi: 10.1007/s12098-011-0483-0
ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับมหาวิทยาลัยเชียงใหม่ และคณาจารย์ท่านอื่นๆในมหาวิทยาลัยฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใด ๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเองแต่ผู้เดียว