Fatigue and Health-related Quality of Life in School-age Children with Cancer Receiving Chemotherapy


  • Rujsara Kaewta Student of Nursing Science, Faculty of Nursing, Chiang Mai University
  • Srimana Niyomkar Assistant Professor, Faculty of Nursing, Chiang Mai University
  • Suthisa Lamchang Associate Professor, Faculty of Nursing, Chiang Mai University


Fatigue, Health-related quality of live, school-age children with cancer


Health-related quality of life in school-age children with cancer receiving chemotherapy is an important aspect of demonstrating the effects of illness from cancer and chemotherapy on the lives of sick children. This descriptive correlational research studied health-related quality of life, and examined the correlation between fatigue and health-related quality of life in school- age children with cancer receiving chemotherapy. The concept of quality of life for health introduced by Ferrans and colleagues with the literature review was used as the study framework. Participants were children with cancer aged 8 to 12 years receiving chemotherapy in the outpatient department and pediatric ward at three tertiary hospitals, northern Thailand from November 2018 to April 2019. A total of 85 participants were selected. The research instruments included a demographic data form for parents, a demographic data form for sick children, the Multidimensional Fatigue Scale and a Health-related Quality of Life Questionnaire for School-age Children. Data were analyzed using descriptive statistics and Pearson’s correlation coefficient.

          The results are as follows.

  1. Fifty-four point one percent of school-age children with cancer receiving chemotherapy had a moderate level of health-related quality of life (=65.48, SD=10.91).
  1. Sick children with low levels of fatigue will have a high level of health-related quality of life with statistical significance (r=.763, p<.001).

            This study demonstrated that fatigue is an important factor correlated to perceived health-related quality of life in school-aged children with cancer receiving chemotherapy. These results provide a guideline for nursing planning to promote health-related quality of life in the target group and can also be used as a basis for further research.


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