Essence of Chicken: Biological Mechanisms, Clinical Evidence, and Applications

Abstract

  Essence of chicken is produced through a temperature and pressure controlled extraction process applied to chicken meat, resulting in a nutrient-dense liquid that is easily digested and rapidly absorbed. It contains several key bioactive components, including essential and non-essential amino acids, short-chain peptides, carnosine, anserine, as well as select vitamins and minerals. Emerging evidence from both animal and human studies suggests that essence of chicken may offer benefits across multiple domains, such as enhancing physical and mental performance, reducing physical and mental fatigue, alleviating stress, and supporting certain aspects of cognitive function. However, findings from meta-analyses indicate that improvements in cognitive outcomes particularly attention and concentration are not consistently demonstrated. These limitations stem largely from weaknesses in primary studies,  including small sample sizes and methodological concerns, underscoring the need for larger, high-quality randomized controlled trials to confirm these effects.   Although the mechanisms of action of essence of chicken are not yet fully elucidated, several hypotheses have been proposed. These include modulation of neurotransmitter systems, antioxidative activity, enhancement of cellular energy metabolism, and regulation of autonomic nervous system balance. It is likely that these effects arise from the synergistic interaction of multiple constituents rather than a single active compound. Nevertheless, caution is warranted in certain populations, especially individuals with allergies to poultry proteins, those with chronic kidney disease, or those who must restrict sodium intake, as some commercial products may contain relatively high levels of protein or sodium that could pose health risks.   This article aims to provide a comprehensive scientific overview of the nutritional composition, potential mechanisms of action, and health effects of essence of chicken in healthy populations, as well as recommendations for safe and appropriate consumption to support holistic well-being.