18-Fluoroestradiol (18F-FES) PET Imaging in ER Positive Breast Cancer

Authors

  • Peerapon Kiatkittikul National Cyclotron and PET Centre, Chulabhorn Hospital
  • Chetsadaporn Promteangtrong National Cyclotron and PET Centre, Chulabhorn Hospital
  • Anchisa Kunawudhi National Cyclotron and PET Centre, Chulabhorn Hospital
  • Dheeratama Siripongsatian National Cyclotron and PET Centre, Chulabhorn Hospital
  • Chanisa Chotipanich National Cyclotron and PET Centre, Chulabhorn Hospital

Keywords:

FES PET, Fluoroestradiol PET, Estrogen receptor, Breast cancer

Abstract

18F-Fluoroestradiol (18F-FES) is an estrogen analogue that has been used for molecular imaging in estrogen receptor (ER) positive breast cancer. In this study are discussed about pharmacokinetic, pharmacodynamic, technical procedure, interpretative criteria, and potential use of 18F-FES in ER positive breast cancer.

In conclusion, 18F-FES PET imaging in ER positive breast cancer is safe and useful for evaluation of ER expression in the whole body, detection of ER positive lesion, and predict treatment response of hormonal therapy. 18F-FES PET imaging cannot replace but can use as complement to 18F-FDG PET imaging due to heterogeneity of ER expression in some ER positive breast cancer patient.

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Published

2021-10-15

How to Cite

1.
Kiatkittikul P, Promteangtrong C, Kunawudhi A, Siripongsatian D, Chotipanich C. 18-Fluoroestradiol (18F-FES) PET Imaging in ER Positive Breast Cancer. J Chulabhorn Royal Acad [Internet]. 2021 Oct. 15 [cited 2024 Mar. 28];3(4):197-212. Available from: https://he02.tci-thaijo.org/index.php/jcra/article/view/252014

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Academic Articles