Bell’s palsy after inactivated COVID-19 vaccination in an adolescent: A case report

Authors

  • Manunya Tandhansakul Department of Pediatrics, Chulabhorn Hospital, Chulabhorn Royal Academy
  • Naruporn Kasemlawan Department of Pediatrics, Chulabhorn Hospital, Chulabhorn Royal Academy
  • Tanawat Petrutchatachart Department of Rehabilitation Medicine, Chulabhorn Hospital, Chulabhorn Royal Academy

Keywords:

Bell’s palsy, Facial palsy, COVID-19, BBIBP-CorV, Inactivated vaccine, High power laser therapy

Abstract

Bell’s palsy has been reported following COVID-19 vaccination in adults. Here, we report a case of an adolescent male with unilateral peripheral facial palsy after receiving the BBIBP-CorV vaccine. An electrodiagnostic study confirmed the diagnosis. The patient made a complete recovery after medical and rehabilitation treatment. Objectives: This is the first case report of Bell’s palsy following the administration of an inactivated COVID-19 vaccine in an adolescent. Study design: A case report. Setting: Chulabhorn Hospital, Lak Si, Bangkok, Thailand. Subject: An adolescent male with unilateral peripheral facial palsy after receiving the BBIBP-CorV vaccine. Methods: We reviewed the patient’s medical record and electrodiagnostic report. Results: A 14-year-old, previously healthy, adolescent male received his 1st dose of inactivated BBIBP-CorV (Sinopharm) COVID-19 vaccine. Five days later, he developed right peripheral facial palsy. He was diagnosed with Bell’s palsy. Clinical signs and symptoms combined with initial and follow-up electrodiagnostic studies confirmed the diagnosis. He was treated for 5 days with oral prednisolone and vitamin B-complex. He received eye care with artificial tears and underwent a rehabilitation program using the bio-stimulation mode of high-power laser therapy (MLS®) combined with standard physiotherapy. Conclusions: Bell’s palsy might be an adverse event associated with the inactivated BBIBP-CorV COVID-19 vaccine in adolescents.

Downloads

Download data is not yet available.

References

Gilden DH. Clinical practice. Bell's palsy. N Engl J Med. 2004;351(13):1323–1331.

Singhi P and Jain V. Bell’s palsy in children. Semin Pediatr Neurol. 2003;10(4):289–297.

Karalok ZS, Taskin BD, Ozturk Z, et al. Childhood peripheral facial palsy. Childs Nerv Syst. 2018;34(5):911–917.

Baugh RF, Basura GJ, Ishii LE, et al. Clinical practice guideline: Bell’s palsy. Otolaryngol Head Neck Surg. 2013;149(3 suppl):S1–S27.

Dumitru D, Amato A, Zwarts M. Electrodiagnostic medicine. second edition. Philadelphia: Hanley&Belfus; 2002.

Pitaro J, Waissbluth S, Daniel SJ. Do children with Bell’ palsy benefit from steroid treatment? A systematic review. Int J Pediatr Otorhinolaryngol. 2012;76(7):921–926.

Yoo HW, Yoon L, Kim HY, et al. Comparison of conservative therapy and steroid therapy for Bell’s palsy in children. Korean J Pediatr. 2018;61(10):332–337.

Ismail AQ, Alake O, Kallappa C. Do oral steroids aid recovery in children with Bell’s palsy? J Child Neurol. 2014;29(10):NP96–NP97.

Rowhani-Rahbar A, Klein NP, Lewis N, et al. Immunization and Bell’s palsy in children: a case-centered analysis. Am J Epidemiol. 2012;175(9):878–885.

Bardage C, Persson I, Örtqvist Å, et al. Neurological and autoimmune disorders after vaccination against pandemic influenza A (H1N1) with a monovalent adjuvanted vaccine: population based cohort study in Stockholm, Sweden. BMJ. 2011;343:d5956.

Wan EYF, Chui CSL, Lai FTT, et al. Bell’s palsy following vaccination with mRNA (BNT162b2) and inactivated (CoronaVac) SARS-CoV-2 vaccines: a case series and nested case-control study. Lancet Infect Dis. 2022;22(1):64–72.

Thonginnetra S, Tawinprai K, Niemsorn K, et al. Safety after BBIBP-CorV (Sinopharm) COVID-19 vaccine in adolescents aged 10-17 years in Thailand. Vaccines. 2022;10:1765.

Preston DC and Shapiro BE. Electromyography and neuromuscular disorders: Clinical-electrophysiologic correlations. third edition. London, UK: Elsevier Saunders; 2013.

Dumitru D, Amato A, Zwarts M. Electrodiagnostic medicine. second edition. Philadelphia: Hanley&Belfus; 2002.

Nishizawa Y, Hoshina Y, Baker V. Bell’s palsy following the Ad26.COV2.S COVID-19 vaccination. QJM. 2021;114(9):657–658.

Wijnans L, Dodd CN, Weibel D, Sturkenboom M. Bell’s palsy and influenza (H1N1) pdm09 containing vaccines: A self-controlled case series. PLoS One. 2017;12(5): e0175539.

Sato K, Mano T, Niimi Y, et al. Facial nerve palsy following the administration of COVID-19 mRNA vaccines: Analysis of a self-reporting database. Int J Infect Dis. 2021;111:310–312.

Hashmi JT, Huang YY, Osmani BZ, et al. Role of low-level laser therapy in neurorehabilitation. PM&R. 2010;2(12 Suppl):S292–S305.

Santamato A, Solfrizzi V, Panza F, et al. Short-term effects of high-intensity laser therapy versus ultrasound therapy in the treatment of people with subacromial impingement syndrome: a randomized clinical trial. Phys Ther. 2009;89(7):643–652.

Mester A. Laser biostimulation. Photomed Laser Surg. 2013;31(6):237–239.

Downloads

Published

2024-04-01

How to Cite

1.
Tandhansakul M, Kasemlawan N, Petrutchatachart T. Bell’s palsy after inactivated COVID-19 vaccination in an adolescent: A case report. J Chulabhorn Royal Acad [Internet]. 2024 Apr. 1 [cited 2024 Sep. 27];6(2):75-81. Available from: https://he02.tci-thaijo.org/index.php/jcra/article/view/261260

Issue

Section

Research Articles