Association of risk level and major adverse cardiovascular events in patients with non-ST elevation myocardial infarction : a clinical assessment using GRACE risk score
Keywords:
Non-ST elevation myocardial infarction (NSTEMI), GRACE risk score, major adverse cardiovascular events (MACE)Abstract
Patients with non-ST elevated myocardial infarction (NSTEMI) are at high risk of developed major adverse cardiovascular events (MACE) during and after hospitalization. This descriptive study examined the association of the risk level and MACE caused by NSTEMI. Risk level was stratified by using the Otago-Southland Global Registry of Acute Coronary Events (GRACE) risk score. All data and GRACE risk indexes were collected from patient record documents. Eligible sample were a total of 176 NSTEMI patients admitted to a 170-bed community hospital during January 1, 2013 to June 30, 2015.
Results revealed that in-hospital mortality rate was 9.09%, mortality rate during six-month after hospital discharge was 14.37%, and overall mortality rate was 22.16%. The increment risk of in-hospital mortality was found in those with moderate (OR = 1.63, 95% CI 0.08-32.92) and severe (OR = 7.86, 95% CI 0.45-138.71) risk groups, compared to the mild risk group. Similarly, the increment risk of mortality during six-month after hospital discharge was found in those with moderate (OR = 2.46, 95% CI 0.29-20.89) and severe (OR = 4.00, 95% CI 0.48-33.08) risk groups. Overall cardiac-cause mortality rate was found the higher risk ratio in those with moderate (OR = 3.20, 95% CI 0.39-26.21) and severe (OR = 8.33, 95% CI 1.05-66.23) risk groups.
Using the Otago-Southland GRACE risk score can be prognostic the clinical outcomes and provides the specific treatment regimens based on each individual patient risk
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