Factors influencing antiplatelet therapy adherence among patients with acute ST- elevation myocardial infarction in post percutaneous coronary intervention

Authors

  • Ketsarin Sriphet Master of Nursing Science (Adult Nursing), Faculty of Nursing, Mahidol University
  • Chongjit Seneha Faculty of Nursing, Mahidol University
  • Sarinrut Sriprasong Faculty of Nursing, Mahidol University
  • Anek Kanoksilp Central Chest Institute of Thailand, Nonthaburi

Keywords:

antiplatelet therapy adherence, cognitive illness, emotional response, patient-provider relationship, patients with acute ST-elevation myocardial infarction

Abstract

            The present study was a predictive correlational research which aimed at investigating the cognitive illness representation, emotional response and patient-provider relationship on antiplatelet therapy adherence among patients with acute ST- elevated myocardial infarction (STEMI) six months to one year post percutaneous coronary intervention (PCI). The study sample consisted of 177 patients with STEMI post PCI at a specialized tertiary hospital in Nontaburi province.  Data were collected by survey of the demographic characteristics questionnaire, the health and medication intake questionnaire, the Brief Illness Perception Questionnaire, Trust in Physician Scale, and the Medication Adherence Report Scale.  Descriptive statistics, Spearman’s rho and logistics regression analysis were used to analyze data.

            The findings revealed that 79.7% of the participants were male with the mean age of 58.75 years old (S.D. = 11.1).  Almost three quarters, or 70.1%, had good medication adherence. Moreover, cognitive illness representation, emotional response and patient-provider relationship could co-predict antiplatelet therapy adherence among patients with STEMI post PCI by 32.3% (Negelkerke R2 = 0.323). Finally, emotional response to illness “fear of relapses” (OR = 1.14, 95%CI = 1.06-1.21, p < 0.001) and relationship between patients and healthcare providers were the two factors that had an influence on antiplatelet therapy adherence (OR = 1.30, 95% CI = 1.15-1.46, p < 0.001) with statistical significance.

            Based on the study findings, it is recommended that nurses should raise the patients’ awareness about chance of relapses and promote the relationship between patients and healthcare providers to ensure antiplatelet adherence therapy among patients with STEMI post PCI.

References

Li J, Li X, Wang Q, Hu S, Wang Y, Masoudi FA, et al. ST-segment elevation myocardial infarction in China from 2001 to 2011 (the China PEACE-Retrospective Acute Myocardial Infarction Study): a retrospective analysis of hospital data. Lancet. 2015; 385(9966): 441-51.

O’Gara PT, Kushner FG, Ascheim DD, Casey DE, Chung MK, De Lemos JA, et al. 2013 ACCF/AHA guideline for the management of ST-elevation myocardial infarction. Circulation. 2013; 127(4): e362- e425.

Ibanez B, James S, Agewall S, Antunes MJ, Bucciarelli-Ducci C, Bueno H, et al. 2017 ESC guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation: the Task force for the management of acute myocardial infarction in patients presenting with ST-segment elevation of the European Society of Cardiology (ESC). Eur Heart J. 2017; 39(2): 119-77.

Bureau of Policy and Strategy.Public Health Statistic 2015. [doccument on the Internet]; 2016.[cited 2016 Jan 16]. Available from: https://bps.moph.go.th/new_bps/sites/default/files/health_statistic 2015.pdf. (in Thai).

Bittl JA, Baber U, Bradley SM, Wijeysundera DN. Duration of dual antiplatelet therapy: a systematic review for the 2016 acc/aha guideline focused update on duration of dual antiplatelet therapy in patients with coronary artery disease: a report of the american college of cardiology/american heart association task force on clinical practice guidelines. J Am Coll Cardiol. 2016; 68(10): 1116-39.

Valgimigli M, Bueno H, Byrne RA, Collet JP, Costa F, Jeppsson A, et al. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS.. Eur J Cardiothorac Surg. 2018 Jan 1;53(1):34-78. doi: 10.1093/ejcts/ezx334.

Raebel MA, Schmittdiel J, Karter AJ, Konieczny JL, Steiner JF. Standardizing terminology and definitions of medication adherence and persistence in research employing electronic databases. Med Care. 2013; 51(83): 1-18.

Sabaté E. Adherence to long-term therapies: Evidence for action: World Health Organization; 2003 [cited 2017 Nov 4]. Available from: http:www.who.int/mediacentre/factsheets/fs307/en/.

Molloy GJ, Messerli-Bürgy N, Hutton G, Wikman A, Perkins-Porras L, Steptoe A. Intentional and unintentional non-adherence to medications following an acute coronary syndrome: a longitudinal study. J Psychosom Res. 2014; 76(5): 430-2.

Pinnarelli L, Mayer F, Bauleo L, Agabiti N, Kirchmayer U, Belleudi V, et al. Adherence to antiplatelet therapy after percutaneous coronary intervention: a population study in a region of Italy. Eur J Cardiovasc Med. 2015; 16(3): 230-7.

Dias A, Pereira C, Monteiro MJ, Santos C. Patients’ beliefs about medicines and adherence to medication in ischemic heart disease. Atencion primaria. 2014; 46(1): 101-6.

Penpimol P, Charoenkitkarn V, Wattanakitkrileart D, Dumavibhat C. the Influence of perceived medication necessity, medication concern, patient-healthcare provider communication, and complexity of medical regimens on medication adherence in patients with acute coronary syndrome after hospitalization. Journal of The Royal Thai Army Nurses. 2016; 17(3): 149-57. (in Thai).

Leventhal H, Diefenbach M, Leventhal EA. Illness cognition: using common sense to understand treatment adherence and affect cognition interactions. Cognit Ther Res. 1992; 16(2): 143-63.

Leventhal H, Phillips LA, Burns E. the Common-sense model of self-regulation (csm): a dynamic framework for understanding illness self-management. J Behav Med. 2016; 39(6): 935-46.

Platt I, Green HJ, Jayasinghe R, Morrissey SA. Understanding adherence in patients with coronary heart disease: illness representations and readiness to engage in healthy behaviours. Aust Psychol. 2014; 49(2): 127-37.

Stafford L, Jackson HJ, Berk M. Illness beliefs about heart disease and adherence to secondary prevention regimens. Psychosom Med. 2008; 70(8): 942-8.

Fennessy MM, DeVon HA, Ryan C, Lopez JJ, Zerwic JJ. Changing illness perceptions and adherence to dual antiplatelet therapy in patients with stable coronary disease. J Cardiovasc Nurs. 2013; 28(6): 573-83.

Mosleh SM, Almalik MM. Illness perception and adherence to healthy behaviour in Jordanian coronary heart disease patients. Eur J Cardiovasc Nurs. 2016; 15(4): 223-30.

Broadbent E, Petrie KJ, Main J, Weinman J. the Brief illness perception questionnaire. J Psychosom Res. 2006; 60(6): 631-7.

Kumar K, Greenfield S, Raza K, Gill P, Stack R. Understanding adherence-related beliefs about medicine amongst patients of south asian origin with diabetes and cardiovascular disease patients: a qualitative synthesis. BMC Endocr Disord. 2016; 16(1): 1-11.

Ens T, Seneviratne C, Jones C, King-Shier K. Factors influencing medication adherence in South Asian people with cardiac disorders: An ethnographic study. Int J Nurs Stud. 2014; 51(11): 1472-81.

Ruangthip R, Wattanakitkrileart D, Charoenkitkarn V, Dumavibhat C. Factors influencing medication adherence in patients with chronic heart failure. Royal Thai Navy Medical Journal. 2017; 44(3): 51-65. (in Thai).

Elder Kkse, Ramamonjiarivelo Z, Wiltshire J, Piper C, Horn WS, Gilbert KL, et al. Trust, medication adherence, and hypertension control in southern african american men. Am J Publ Health Res. 2012; 102(12): 2242-5.

Prommaloon S, Wattanakitkrileart D, Charoenkitkarn V, Peerapatdit T. Factors influencing insulin adherence in patients with type 2 diabetes. Nursing Science Journal of Thailand. 2017; 35(1): 61-71. (in Thai).

Faul F, Erdfelder E, Buchner A, Lang A-G. Statistical power analyses using g*power 3.1.7 [computer software] 2013 [cited 2018 Nov 5]. Available from: https://www.softpedia.com/get/Science-CAD/G-Power.shtml.

Brodaty H, Pond D, Kemp NM, Luscombe G, Harding L, Berman K, et al. The GPCOG: a new screening test for dementia designed for general practice. J Am Geriatr Soc. 2002; 50(3): 530-4.

Griffiths J, Putthioi S, Pongsuksri M. the General Practitioner Assessmentof Cognition; GP-COG (thai version): validity and reliability. Poster session presented at Rewinding the aging clock. 9th Pan-Pacific Conferenceon Rehabilitation cum 21st Annual Congressof Gerontology; 2014 Nov 29-30; Jockey Club Auditorium, the Hong Kong Polytechnic University. Hong Kong, China.

Thepphawan P, Watthnakitkrileart D, Pongthavornkamol K, Dumavibhat C. Cognitive representation, emotional responses and hospitalization experience in predicting decision makingfor receiving treatment among patients with acute coronary syndrome. Nursing Science Journal of Thailand. 2011; 29(2): 111-9. (in Thai).

Yan J, You L-M, He J-G, Wang J-F, Chen L, Liu B-L, et al. Illness perception among Chinese patients with acute myocardial infarction. Patient Educ Couns. 2011; 85(3): 398-405.

Anderson LA, Dedrick RF. Development of the trust in physician scale: a measure to assess interpersonal trust in patient-physician relationships. Psychol Rep. 1990; 67(3_suppl): 1091-100.

Horne R, Weinman J. Patients' beliefs about prescribed medicines and their role in adherence to treatment in chronic physical illness. J Psychosom Res. 1999; 47(6): 555-67.

Ferdinand KC, Senatore FF, Clayton-Jeter H, Cryer DR, Lewin JC, Nasser SA, et al. Improving medication adherence in cardiometabolic disease: practical and regulatory implications. J Am Coll Cardiol. 2017 Jan 31;69(4):437-51.doi:10.1016/j.jacc.2016.11.034.

Junehag L, Asplund K, Svedlund M. Perceptions of illness, lifestyle and support after an acute myocardial infarction. Scand J Caring Sci. 2014;28 (2): 289-96.

Rashid MA, Edwards D, Walter FM, Mant J. Medication taking in coronary artery disease: a systematic review and qualitative synthesis. Ann Fam Med. 2014; 12(3): 224-32.

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Published

2020-03-07

How to Cite

1.
Sriphet K, Seneha C, Sriprasong S, Kanoksilp A. Factors influencing antiplatelet therapy adherence among patients with acute ST- elevation myocardial infarction in post percutaneous coronary intervention. Thai J Cardio-Thorac Nurs. [Internet]. 2020 Mar. 7 [cited 2024 Dec. 22];30(2):111-25. Available from: https://he02.tci-thaijo.org/index.php/journalthaicvtnurse/article/view/240344

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Research Articles