Sex difference in metabolic syndrome, metabolic risk components, and amount among non-obese hypertension patients


  • Orapen Sukhavulli Walailak University School of Nursing, Nakhon Si Thammarat
  • Chonchanok Bunsuk Walailak University School of Nursing, Nakhon Si Thammarat


hypertension, metabolic syndrome, sex-difference


       This descriptive and comparison study to examine whether nonobese hypertension women and men had differences in prevalence of MetS, components, and amount of metabolic risk. Sample was 292 nonobese hypertensions who were treated at four primary care units in Nakhon Si Thammarat province, from 2017 to 2018. An Asia criterion of a body mass index of <25.0 kg/m2 was defined nonobese. MetS was defined by using the American Heart Association and the National Heart Lung and Blood Institute (AHA/NHLBI), which a cut-off waist circumference based on an Asia criterion. Univariate logistic model was performed to test sex difference.    

      Results revealed rate of MetS in overall, women and men were 66% (95%CI 60.3-70.5), 73.7% (95%CI 67.2-80.2) and 48.9 % (95%CI 39.1-59.3), respectively. In the age-adjusted model, we found the higher prevalence of MetS among women than did men (AOR 2.99 [95%CI 1.77-5.04], p < 0.001). Women had higher prevalence of low high-density lipoprotein (AOR 3.11 [95%CI 1.86-5.22], p < 0.001), and abdominal obesity (AOR 5.65 [95%CI 3.13-10.19], p < 0.001), compared with men. Whereas, the prevalence of hypertriglyceridemia, and hyperglycemia were not differences. More women than did men had at least two-to at least four, and tend to have had five amount number of metabolic risk components. 

      Sex differences in MetS would be considered in order to reduce cardiovascular risk among nonobese hypertensions. Women had higher risk than did men. Clinical management focused on abdominal obesity and dyslipidaemia are needed in women.


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