Factors predicting quality of life among older adults with advanced cancer receiving palliative care


  • Khuanta Wongketkit The Student of Master of Nursing Science (Gerontological Nursing), Faculty of Nursing, Mahidol University
  • Virapan Wirojratana Department of Fundamental Nursing, Faculty of Nursing, Mahidol University
  • Wallada Chanruangvanich Department of Surgical Nursing, Faculty of Nursing, Mahidol University


quality of life, older adults, advanced cancer, performance status, satisfaction, financial burden


This predictive correlational research aimed at studying the influence of performance status, satisfaction with information, and perceived financial burden on the quality of life among older adults with advanced cancer receiving palliative care. The subjects were 85 older adults with advanced cancer. Data were collected by using the questionnaires including demographic data, quality of life, performance status, satisfaction with information, and perceived financial burden. Predictive power was analyzed by using multiple regression statistics.

According to the findings, most of the sample, 32.9%, had lung cancer. The overall quality of life was moderate (Mean= 62.05, SD=21.38), and performance status (KPS score 70-80) was 52.9 %. satisfaction with information (Mean= 70.59, SD=21.46) and perceived financial burden were low (Mean= 25.94, SD=31.19). The factors of performance status, satisfaction with information, and perceived financial burden could together explain 53% of the variance of quality of life among older adults with advanced cancer (adjusted R² = 0.51, R² = 0.53, F = 30.05, p < 0.001). The factors predicting quality of life with statistical significance were performance status (β = 0.55, p < 0.01) and perceived financial burden (β = - 0.27, p < 0.01)       

The study findings suggest that nurses should develop care activities that promote the maintenance of performance status and assess the perceived financial burden, then provide support and useful resources. This will promote the efficient transition among older adults with advanced cancer who received palliative care and result in a better quality of life.


World Health Organization. Cancer [Internet]. 2017 [cited 2017 Jul 10]. Available from: https://www. who. int /health-topics/cancer#tab=tab_1

National Cancer Institute. Hospital based cancer registry 2017. Bangkok: Pornsup Printing; 2019. (in Thai)

White MC, Holman DM, Boehm JE, Peipins LA, Grossman M, Henley SJ. Age and cancer risk: a potentially modifiable relationship. Am J Prev Med. 2014;46(301):S7-15.

Park SA, Chung SH, Lee Y. Factors influencing the quality of life of patients with advanced cancer. Asian Nurs Res. 2017;33:108-12.

Trakoolngamden B, Wongteerasup S. Predicting factors of quality of life among patients with terminal cancer at out–patient department of hospitals in medical service department, bangkok metropolitan and faculty of medi-cine vajira hospital, Navamindradhiraj University. Kuakarun Journal of Nursing. 2018;23(2):199-216. (in Thai)

Teerathongdee K, Ronnarithivichai C, Thongchareon V, Pongthavornkamol K. Factors predicting quality of life in aged patients with colorectal cancer after stomal surgery. Thai Cancer Journal. 2014;34(2):68-78. (in Thai)

Husson O, Oerlemans S, Mols F, Smeets RE, Poortmans PM, van de Poll-Franse LV. Satisfaction with in-formation provision is associated with baseline but not with follow-up quality of life among lymphoma patients: Results from the PROFILES registry. Acta Oncol. 2014;53(7):917-26.

Nicolaisen M, Muller S, Patel HR, Hanssen TA. Quality of life and satisfaction with information after radical pros-tatectomy, radical external beam radiotherapy and postoperative radiotherapy: a long-term follow-up study. J Clin Nurs. 2014;23(23-24):3403-14.

Pongthavornkamol K, Lekdamrongkul P, Wanawarodom P, Ratchawong W. Relationships between social support, financial status, health-promoting behaviors, and quality of life among women with breast cancer un-dergoing radiation treatment. Nursing Science Journal of Thailand. 2014;32(1):15-27. (in Thai)

Delgado-Guay M, Ferrer J, Rieber AG, Rhondali W, Tayjasanant S, Ochoa J, et al. Financial distress and its associations with physical and emotional symptoms and quality of life among advanced cancer patients. The Oncologist. 2015;20(9):1092-8.

Kale HP, Carroll NV. Self-reported financial burden of cancer care and its effect on physical and mental health-related quality of life among US cancer survivors. Cancer. 2016;122(8):283-9.

Bostock S, Steptoe A. Association between low functional health literacy and mortality in older adults: longitu-dinal cohort study. BMJ. 2012; 344:e1602 doi:10.1136/bmj. e1602

Meleis A. Transitions Theory Middle-Range and Situation-Specific Theories in nursing research and practice. 1st Edition. New York: Springer Publishing Company; 2010.

Griffiths J, Putthinoi S, Pongsaksri M. The general practitioner assessment of cognition; GPCOG (Thai Ver-sion): validity and reliability. Chiang Mai: Department of Occupational Therapy, Faculty of Associated Medical Sciences, Chiang Mai University; 2013.

Tiansaard J, Chaiviboontham S, Phinitkhajorndech N. Perception of symptom burden, financial burden, and quality of life in patients with end stage renal disease undergoing hemodialysis. Ramathibodi Nursing Journal. 2017;23(1):60-77. (in Thai)

Brodaty H, Pond D, Kemp NM, Luscombe G, Harding L, Berman K, et al. The GPCOG: a new screening test for dementia designed for general practice. J Am Geriatr Soc. 50(3): 530-34.

Fayers P, Bottomley A. Quality of life research within the EORTC-the EORTC QLQ-C30. European organisa-tion for research and treatment of cancer. Eur J Cancer. 2002;38 Suppl 4: S125-33.

Silpakit C, Sirilerttrakul S, Jirajarus M, Sirisinha T, Sirachainan E, Ratanatharathorn V. The European Organiza-tion for Research and Treatment of Cancer Quality of Life Questionnaire (EORTC QLQ-C30): Validation study of the Thai version. Qual Life Res. 2006;15(1):167-72.

Arraras JI, Greimel E, Sezer O, Chie WC, Bergenmar M, Costantini A, et al. An international validation study of the EORTC QLQ-INFO25 questionnaire: an instrument to assess the information given to cancer patients. Eur J Cancer. 2010;46(15):2726-38.

Mor V, Laliberte L, Morris JN, Wiemann M. The Karnowski Performance Status Scale. An examination of its reliability and validity in a research setting. Cancer.1984;53 (9):2002-7.

Junsomkoy C, Wirojratana V, Chanruangvanich W. Relationships between basic conditioning factors, symptom severity, palliative self-care behaviors and quality of life in older adults with advanced cancer receiving chemo-therapy. Journal of The Royal Thai Army Nurses. 2018;19:108-17. (in Thai)

Chen Y, Xiao Y, Yang Y, et al. Decomposing contribution of age and non-age factors to rapid growth of lung cancer in Xuanwei over past 30 years. BMC Public Health. 2015;15:1116-1116.

Leppert W, Majkowicz M, Forycka M, Mess E, Zdun-Ryzewska A. Quality of life assessment in advanced cancer patients treated at home, an inpatient unit, and a day care center. Onco Targets Ther. 2014;8(7):687-95.

Shallwani SM, Simmonds MJ, Kasymjanova G, Spahija J. Quality of life, symptom status and physical performance in patients with advanced non-small cell lung cancer undergoing chemotherapy: an exploratory analysis of secondary data. Lung cancer. 2016; 99:69-75.




How to Cite

Wongketkit K, Wirojratana V, Chanruangvanich W. Factors predicting quality of life among older adults with advanced cancer receiving palliative care. Thai J Cardio-Thorac Nurs. [Internet]. 2022 Sep. 24 [cited 2024 Jul. 20];33(1):117-31. Available from: https://he02.tci-thaijo.org/index.php/journalthaicvtnurse/article/view/251175



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