Prevalence and gender difference in bleeding events among acute coronary syndrome patients after percutaneous coronary intervention
Keywords:
acute coronary syndrome, post percutaneous coronary intervention, bleeding eventAbstract
The purposes of this study were to explore the prevalence and gender difference in bleeding events among acute coronary syndrome (ACS) patients after percutaneous coronary intervention (PCI) during hospitalization. A total of 375 eligible ACS patients with PCI were enrolled as a sample. The secondary data reviews, annual medical records of a tertiary hospital, were applied for data collection. Frequency, percentage, and standard deviation statistics were used to analyze descriptive data. Chi-square and fisher’s exact test were applied to analyze the association between factors and bleeding events, whereas gender difference in bleeding events prediction was analyzed by binary logistic regression.
Results showed that most of the patients were male 76.8%, average age of 61.1±12.5 years. The bleeding events were total 40.5% (95% CI: 0.44-.0.58), female 47.1 % (95%CI: 0.47-0.79), and male 38.5 % (95%CI: 0.39-0.54), respectively. Factors, including age, place of illness onset, and shock event were significant association with bleeding events (p = .000, .007, .008, respectively). Gender difference for bleeding events, age-associated with bleeding events both female and male (p = .003, .019, respectively). Male who presented shock associated with bleeding events (p-value= .008). The bleeding tendency of females was more than males (OR 1.421, 95%CI: 0.877-2.304, p= .154),
The findings indicated that ACS patients with PCI, involving females and/or > 50 years and/or males with shock, should be closely provided observation and eariler care for bleeding prevention during hospitalization.
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