Water sorption, solubility and monomer elution from three commercial orthodontic adhesives

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Amnaj Likitkulthanaporn


Objectives: The aims of this study were to study the water sorption, water solubility, and elution of three monomers Bis-GMA, TEGDMA, and BPA of three commercial orthodontic adhesives up to 7 days.

Materials and methods: The water sorption, water solubility and monomer elution from three commercial adhesives; one chemically cured; Unite (Unitek Corp., Monrovia, CA, USA), two light-cured;  Enlight (Ormco, Glendora, California, USA), and Grengloo (Ormco, Glendora, California, USA) were determined at four interval times of 1,3,5, and 7 days immersion. The adhesive specimen was prepared by polymerization in a cylindrical stainless steel mold with a diameter of 10 mm and 1 mm thickness. The water sorption and solubility protocol were done according to ISO 4049 specification. The concentration of Bis-GMA, TEGDMA, and BPA from the immersion medium was determined using High-performance liquid chromatography (HPLC). One-way ANOVA followed by Dunnett T3 test for water sorption and Tukey’s for elution test were done for multiple comparisons.

Results: Water sorption and water solubility were found to increase with storage time. It was found that they had similar water sorption and water solubility at 1 day (p>0.05) but differences were found at other time intervals (p<0.05). All adhesives had significantly differences in water sorption and solubility between 1 day and 7 days (p<0.05). Enlight and Unite had Bis-GMA, TEGDMA, and BPA elution at all time intervals, however in varied amount. Grengloo contains no Bis-GMA in the immersion medium at all time intervals. They were significantly differences among elution of the different adhesives at the same time (p<0.05) and among time intervals of the same adhesive (p<0.05) except Bis-GMA elution of Enlight at 1 day and 7 days (p>0.05) and BPA elution of Unite at 1 day and 7 days (p<0.05) which had similar results. Pearson’s correlation coefficient were found high correlation between water sorption and solubility (R2 =0.988). Only TEGDMA at 3 and 5 d found correlation with water sorption  (R2=0.754), and sol  (R2=0.878)    

Conclusion:  Water sorption and solubility of light-cure and chemically cured adhesives increase with storage time. The amount of monomer leached from the polymerized specimen from all adhesives seems to be varied.


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Likitkulthanaporn A. Water sorption, solubility and monomer elution from three commercial orthodontic adhesives. M Dent J [Internet]. 2018 Apr. 30 [cited 2023 Dec. 8];38(1):45-56. Available from: https://he02.tci-thaijo.org/index.php/mdentjournal/article/view/179243
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