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Objective: to compare the incidence of allergic contact dermatitis between styrenic thermoplastic elastomers (S-TPEs) and latex sheets in patients scheduled for endodontic treatment by patch testing.
Material and method: A total of 100 subjects were tested with the substances in S-TPEs group (S-TPEs sheet, Styrene isoprene styrene-SIS, Styrene butylene styrene-SBS, dye powder) and latex group (latex sheet, thiuram-mix, mercapto-mix, mercaptobenzothiazole, zinc diethyldithiocarbamate-ZDEC, zinc dibutyldithiocarbamate-ZDBC). The reactions were evaluated at 48 and 96 hours after application of the test materials to the skin of the upper arm.
Results: For the S-TPEs group, none of the subjects showed positive allergic reactions to S-TPEs sheet and its compositions at 48 and 96 hours. For the latex group, seven subjects (7%) had positive allergic reactions to latex sheet at 48 hours, and one (1%) at 96 hours. One subject (1%) showed reactions to thiuram-mix, mercapto-mix, and mercaptobenzothiazole at 48 and 96 hours, one subject (1%) reacted to thiuram-mix, and one subject (1%) reacted to ZDEC at 96 hours. Upon comparison between positive allergic reactions of S-TPEs and latex sheets, a significant difference was demonstrated at 48 hours (p<0.05), but not at 96 hours.
Conclusion: S-TPEs sheet did not cause allergic contact dermatitis, while latex sheet did in a number of subjects.
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