Long-term effect of nasoalveolar molding on skeletal and dental development in patients with oral clefts; a systematic review and meta-analysis
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Abstract
Objective: This study aimed to analyze the treatment effects of pre-surgical nasoalveolar molding (PNAM) on cephalometric characteristics and dentoalveolar outcome for patients with non-syndromic unilateral cleft lip and palate by conducting a systematic review and meta-analysis.
Materials and Methods: Five electronic databases and two journals were searched up through October 2021. Studies comparing treatment results between PNAM and non-PNAM treatment protocols were selected for analyses. Cephalometric characteristics and dentoalveolar outcome were outcomes of interest. Data extraction, methodological quality assessment, risk of bias assessment, and meta-analysis were performed.
Results: Four retrospective cohort studies were selected for a qualitative review and meta-analysis. The risk of bias assessment was moderate for all studies. Treatment results from patients who underwent PNAM were not significantly different from other treatment protocols.
Conclusion: This study found that PNAM does not improve cephalometric characteristics and dentoalveolar outcomes.
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References
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